A large amount of evidence has demonstrated the power of exercise to support cognitive
function, the effects of which can last for considerable time. An emerging line of scientific …

Aging is the greatest risk factor for most diseases including cancer, cardiovascular disorders,
and neurodegenerative disease. There is emerging evidence that interventions that improve …

Abstract Background Late-onset Alzheimer's disease (AD) is a complex multifactorial
affliction, the pathogenesis of which is thought to involve gene-environment interactions that …

The decline of brain function during aging is associated with epigenetic changes, including
DNA methylation. Lifestyle interventions can improve brain function during aging, but their …

Cumulative evidence shows that modifications in lifestyle factors constitute an effective
strategy to modulate molecular events related to neurodegenerative diseases, confirming …

Parkinson's disease (PD) is a neurodegenerative disorder with a complex etiology and
increasing prevalence worldwide. As PD is influenced by a combination of genetic and …

Psychiatric disorders are clinically heterogeneous and debilitating chronic diseases
resulting from a complex interplay between gene variants and environmental factors …

Aging entails a progressive decline of cognitive abilities. However, since the brain is
endowed with considerable plasticity, adequate stimulation can delay or partially …

With the increase in life expectancy, aging and age-related cognitive impairments are
becoming one of the most important issues for human health. At the same time, it has been …

Aim: The present study investigated the link between peripheral DNA methylation (DNAm),
cognitive impairment and brain aging. Methods: We tested the association between blood …