Neuroinflammation induced by lipopolysaccharide causes cognitive impairment in mice
J Zhao, W Bi, S Xiao, X Lan, X Cheng, J Zhang, D Lu… - Scientific reports, 2019 - nature.com
In this study, we investigated lipopolysaccharide (LPS)-induced cognitive impairment and
neuroinflammation in C57BL/6J mice by using behavioral tests, immunofluorescence …
neuroinflammation in C57BL/6J mice by using behavioral tests, immunofluorescence …
AIF1: function and connection with inflammatory diseases
D De Leon-Oliva, C Garcia-Montero, O Fraile-Martinez… - Biology, 2023 - mdpi.com
Simple Summary Allograft inflammatory factor 1 (AIF1) is a calcium-binding protein that
participates in intracellular processes such as phagocytosis, membrane ruffling and F-actin …
participates in intracellular processes such as phagocytosis, membrane ruffling and F-actin …
Macrophages: an elusive yet emerging therapeutic target of atherosclerosis
Macrophages are central to the initiation and progression of atherosclerosis and thus can be
very appropriate targets for therapy. Cell adhesion molecules mediating monocytes …
very appropriate targets for therapy. Cell adhesion molecules mediating monocytes …
T cell costimulation blockade blunts pressure overload-induced heart failure
Heart failure (HF) is a leading cause of mortality. Inflammation is implicated in HF, yet clinical
trials targeting pro-inflammatory cytokines in HF were unsuccessful, possibly due to …
trials targeting pro-inflammatory cytokines in HF were unsuccessful, possibly due to …
The potential ameliorative impacts of cerium oxide nanoparticles against fipronil-induced hepatic steatosis
Fipronil (FIP) is a phenylpyrazole insecticide that is commonly used in agricultural and
veterinary fields for controlling a wide range of insects, but it is a strong environmentally toxic …
veterinary fields for controlling a wide range of insects, but it is a strong environmentally toxic …
Role of AIF-1 in the regulation of inflammatory activation and diverse disease processes
YY Zhao, DJ Yan, ZW Chen - Cellular immunology, 2013 - Elsevier
Abstract Allograft Inflammatory Factor-1 (AIF-1) is a 17 kDa cytoplasmic, calcium-binding,
inflammation-responsive scaffold protein that is mainly expressed in immunocytes. AIF-1 …
inflammation-responsive scaffold protein that is mainly expressed in immunocytes. AIF-1 …
Allograft inflammatory factor-1/Ionized calcium-binding adapter molecule 1 is specifically expressed by most subpopulations of macrophages and spermatids in testis
C Köhler - Cell and tissue research, 2007 - Springer
Ionized calcium-binding adapter molecule 1 (Iba1) is a 147-amino-acid calcium-binding
protein widely in use as a marker for microglia. It has actin-crosslinking activity and is …
protein widely in use as a marker for microglia. It has actin-crosslinking activity and is …
Effects of the fibroblast activation protein inhibitor, PT100, in a murine model of pulmonary fibrosis
C Egger, C Cannet, C Gérard, T Suply, I Ksiazek… - European journal of …, 2017 - Elsevier
Bleomycin (BLM) induced lung injury is detectable in C57BL/6 mice using magnetic
resonance imaging (MRI). We investigated the effects of the fibroblast activation protein …
resonance imaging (MRI). We investigated the effects of the fibroblast activation protein …
[HTML][HTML] The role of tumor-associated macrophages in primary hepatocellular carcinoma and its related targeting therapy
L Deng, K He, Y Pan, H Wang, Y Luo… - International Journal of …, 2021 - ncbi.nlm.nih.gov
Liver macrophages consist of ontogenically distinct populations termed Kupffer cells and
monocyte-derived macrophages. Tumor-associated macrophages (TAMs) …
monocyte-derived macrophages. Tumor-associated macrophages (TAMs) …
Acetaminophen-induced rat hepatotoxicity based on M1/M2-macrophage polarization, in possible relation to damage-associated molecular patterns and autophagy
Y Tsuji, M Kuramochi, HM Golbar, T Izawa… - International Journal of …, 2020 - mdpi.com
Overdose of acetaminophen (APAP), an antipyretic drug, is an important cause of liver
injury. However, the mechanism in the rat model remains undetermined. We analyzed APAP …
injury. However, the mechanism in the rat model remains undetermined. We analyzed APAP …