• The specific situation of the patient. Unless otherwise provided for by national regulations,
off-label use of medication should be limited to situations where it is in the patient's interest …

Healthcare-associated infections (HAIs) are caused by nosocomial pathogens. HAIs have
an immense impact not only on developing countries but also on highly developed parts of …

After initially hypothesizing a positive relationship between use of renin-angiotensin-
aldosterone system inhibitors and risk of coronavirus disease 2019 (COVID-19), more recent …

Background Antibiotic prophylaxis (AP) before invasive dental procedures (IDPs) is
recommended to prevent infective endocarditis (IE) in those at high IE risk, but there are …

Background From the beginning of the COVID-19 pandemic, age (most importantly), male
gender and various comorbidities were found to be associated with severe forms of COVID …

Objective Antibiotic prophylaxis is recommended before invasive dental procedures to
prevent endocarditis in those at high risk, but supporting data are sparse. We therefore …

The annual incidence of infective endocarditis (IE) is estimated to be between 15 and 80
cases per million persons in population-based studies. The incidence of IE is markedly …

Background: There is little information concerning infective endocarditis (IE) in patients with
bicuspid aortic valve (BAV) or mitral valve prolapse (MVP). Currently, IE antibiotic …

Objectives Infective endocarditis is a life-threatening complication of congenital heart
disease (CHD), but there are few studies concerning the contemporary risk profile …

Objectives Infective endocarditis (IE) is a devastating disease with a 50% 1-year mortality
rate. In recent years, medical authorities across the globe advised stricter criteria for …