Acromegaly: clinical features at diagnosis

L Vilar, CF Vilar, R Lyra, R Lyra, LA Naves - Pituitary, 2017 - Springer
Background Acromegaly is a rare and underdiagnosed disorder caused, in more than 95%
of cases, by a growth hormone (GH)-secreting pituitary adenoma. The GH hypersecretion …

[HTML][HTML] Acromegaly

P Chanson, S Salenave - Orphanet journal of rare diseases, 2008 - Springer
Acromegaly is an acquired disorder related to excessive production of growth hormone (GH)
and characterized by progressive somatic disfigurement (mainly involving the face and …

Acromegaly: an endocrine society clinical practice guideline

L Katznelson, ER Laws Jr, S Melmed… - The Journal of …, 2014 - academic.oup.com
Objective: The aim was to formulate clinical practice guidelines for acromegaly. Participants:
The Task Force included a chair selected by the Endocrine Society Clinical Guidelines …

[图书][B] Oral pathology: clinical pathologic correlations

JA Regezi, J Sciubba, RCK Jordan - 2016 - books.google.com
Diagnose oral diseases quickly and accurately! Oral Pathology: Clinical Pathologic
Correlations, 7th Edition presents diseases and conditions by appearance and presentation …

[HTML][HTML] American Association of Clinical Endocrinologists medical guidelines for clinical practice for the diagnosis and treatment of acromegaly-2011 update

L Katznelson, JLD Atkinson, DM Cook… - Endocrine …, 2011 - endocrinepractice.org
AACE= American Association of Clinical Endocrinologists; BEL=“best evidence” level;
BMD= bone mineral density; CPAP= continuous positive airway pressure; CPG= clinical …

Transsphenoidal microsurgery for growth hormone-secreting pituitary adenomas: initial outcome and long-term results

A Abosch, JB Tyrrell, KR Lamborn… - The Journal of …, 1998 - academic.oup.com
Treatment of acromegaly has long been recognized as necessary to relieve symptoms, halt
progression of deformities, and decompress the sella turcica. More recently, treatment …

Features at diagnosis of 324 patients with acromegaly did not change from 1981 to 2006: acromegaly remains under‐recognized and under‐diagnosed

TJ Reid, KD Post, JN Bruce, M Nabi Kanibir… - Clinical …, 2010 - Wiley Online Library
Background Traditionally, acromegaly evaded diagnosis until in its clinically obvious later
stages when treatment is more difficult. Over the last 25 years diagnostic tests have …

[HTML][HTML] The relative roles of growth hormone and IGF-1 in controlling insulin sensitivity

DR Clemmons - The Journal of clinical investigation, 2004 - Am Soc Clin Investig
IGF-1 and growth hormone (GH) interact with insulin to modulate its control of carbohydrate
metabolism. A new study (see the related article beginning on page 96) shows that blocking …

[HTML][HTML] 60 years of neuroendocrinology: acromegaly

C Capatina, JAH Wass - Journal of Endocrinology, 2015 - joe.bioscientifica.com
Acromegaly (ACM) is a chronic, progressive disorder caused by the persistent
hypersecretion of GH, in the vast majority of cases secreted by a pituitary adenoma. The …

Morbidity after long-term remission for acromegaly: persisting joint-related complaints cause reduced quality of life

NR Biermasz, AM Pereira, JWA Smit… - The Journal of …, 2005 - academic.oup.com
Active acromegaly is associated with significant comorbidity and reduced quality of life.
However, the prevalence of comorbidity after long-term remission is not established …