Epigenetic regulation of ACE2, the receptor of the SARS-CoV-2 virus1
TH Beacon, GP Delcuve, JR Davie - Genome, 2021 - cdnsciencepub.com
The angiotensin-converting enzyme 2 (ACE2) is the receptor for the three coronaviruses
HCoV-NL63, SARS-CoV, and SARS-CoV-2. ACE2 is involved in the regulation of the renin …
HCoV-NL63, SARS-CoV, and SARS-CoV-2. ACE2 is involved in the regulation of the renin …
Employing core regulatory circuits to define cell identity
N Almeida, MWH Chung, EM Drudi, EN Engquist… - The EMBO …, 2021 - embopress.org
The interplay between extrinsic signaling and downstream gene networks controls the
establishment of cell identity during development and its maintenance in adult life. Advances …
establishment of cell identity during development and its maintenance in adult life. Advances …
Dynamic enhancer landscapes in human craniofacial development
The genetic basis of human facial variation and craniofacial birth defects remains poorly
understood. Distant-acting transcriptional enhancers control the fine-tuned spatiotemporal …
understood. Distant-acting transcriptional enhancers control the fine-tuned spatiotemporal …
[HTML][HTML] FOXO3 on the road to longevity: lessons from SNPs and chromatin hubs
P Sanese, G Forte, V Disciglio, V Grossi… - Computational and …, 2019 - Elsevier
Health span is driven by a precise interplay between genes and the environment. Cell
response to environmental cues is mediated by signaling cascades and genetic variants that …
response to environmental cues is mediated by signaling cascades and genetic variants that …
Genetic marker discovery in complex traits: a field example on fat content and composition in pigs
Among the large number of attributes that define pork quality, fat content and composition
have attracted the attention of breeders in the recent years due to their interaction with …
have attracted the attention of breeders in the recent years due to their interaction with …
The noncoding genome and hearing loss
KB Avraham, L Khalaily, Y Noy, L Kamal, T Koffler-Brill… - Human genetics, 2022 - Springer
The age of sequencing has provided unprecedented insights into the human genome. The
coding region of the genome comprises nearly 20,000 genes, of which approximately 4000 …
coding region of the genome comprises nearly 20,000 genes, of which approximately 4000 …
DNA methylation of enhancer elements in myeloid neoplasms: think outside the promoters?
Gene regulation through DNA methylation is a well described phenomenon that has a
prominent role in physiological and pathological cell-states. This epigenetic modification is …
prominent role in physiological and pathological cell-states. This epigenetic modification is …
Epigenetics in the primary biliary cholangitis and primary sclerosing cholangitis
AC Cheung, NF LaRusso, GJ Gores… - Seminars in liver …, 2017 - thieme-connect.com
Epigenomics, the study of modifications to genetic material that do not alter the underlying
DNA sequence, is generating increasing interest as a means to help clarify disease …
DNA sequence, is generating increasing interest as a means to help clarify disease …
Loss of Monoallelic Expression of IGF2 in the Adult Liver Via Alternative Promoter Usage and Chromatin Reorganization
In mammals, genomic imprinting operates via gene silencing mechanisms. Although
conservation of the imprinting mechanism at the H19/IGF2 locus has been generally …
conservation of the imprinting mechanism at the H19/IGF2 locus has been generally …
Integration of chromosome locations and functional aspects of enhancers and topologically associating domains in knowledge graphs enables versatile queries about …
J Mulero-Hernández, V Mironov… - Nucleic Acids …, 2024 - academic.oup.com
Abstract Knowledge about transcription factor binding and regulation, target genes, cis-
regulatory modules and topologically associating domains is not only defined by functional …
regulatory modules and topologically associating domains is not only defined by functional …