The Ruminant Telomere-to-Telomere (RT2T) Consortium

TS Kalbfleisch, SD McKay, BM Murdoch, DL Adelson… - Nature Genetics, 2024 - nature.com
Abstract Telomere-to-telomere (T2T) assemblies reveal new insights into the structure and
function of the previously 'invisible'parts of the genome and allow comparative analyses of …

Formation, structure, and function of extra‐skeletal bones in mammals

A Nasoori - Biological Reviews, 2020 - Wiley Online Library
This review describes the formation, structure, and function of bony compartments in antlers,
horns, ossicones, osteoderm and the os penis/os clitoris (collectively referred to herein as …

[HTML][HTML] Genomics of adaptive evolution in the woolly mammoth

D Díez-del-Molino, M Dehasque, JC Chacón-Duque… - Current Biology, 2023 - cell.com
Ancient genomes provide a tool to investigate the genetic basis of adaptations in extinct
organisms. However, the identification of species-specific fixed genetic variants requires the …

Demographic history, adaptation, and NRAP convergent evolution at amino acid residue 100 in the world northernmost cattle from Siberia

L Buggiotti, AA Yurchenko, NS Yudin… - Molecular Biology …, 2021 - academic.oup.com
Native cattle breeds represent an important cultural heritage. They are a reservoir of genetic
variation useful for properly responding to agriculture needs in the light of ongoing climate …

RGD v2. 0: a major update of the ruminant functional and evolutionary genomics database

W Fu, R Wang, HA Nanaei, J Wang, D Hu… - Nucleic Acids …, 2022 - academic.oup.com
Abstract Ruminant Genome Database (RGD; http://animal. nwsuaf. edu. cn/RGD) provides
visualization and analysis tools for ruminant comparative genomics and functional …

[HTML][HTML] A highland-adaptation mutation of the Epas1 protein increases its stability and disrupts the circadian clock in the plateau pika

N Liu, H Tian, Z Yu, H Zhao, W Li, D Sang, K Lin, Y Cui… - Cell Reports, 2022 - cell.com
Summary The Qinghai-Tibet Plateau (QTP) harbors hundreds of species well adapted to its
extreme conditions, including its low-oxygen (hypoxic) atmosphere. Here, we show that the …

[HTML][HTML] Genome sequence and comparative analysis of reindeer (Rangifer tarandus) in northern Eurasia

M Weldenegodguad, K Pokharel, Y Ming… - Scientific reports, 2020 - nature.com
Reindeer are semi-domesticated ruminants that have adapted to the challenging northern
Eurasian environment characterized by long winters and marked annual fluctuations in …

[HTML][HTML] Normal Light-Dark and Short-Light Cycles Regulate Intestinal Inflammation, Circulating Short-chain Fatty Acids and Gut Microbiota in Period2 Gene Knockout …

Y Zhen, L Ge, Q Xu, L Hu, W Wei, J Huang… - Frontiers in …, 2022 - frontiersin.org
Regular environmental light–dark (LD) cycle-regulated period circadian clock 2 (Per2) gene
expression is essential for circadian oscillation, nutrient metabolism, and intestinal …

[HTML][HTML] Life at high latitudes does not require circadian behavioral rhythmicity under constant darkness

E Bertolini, FK Schubert, D Zanini, H Sehadova… - Current Biology, 2019 - cell.com
Nearly all organisms evolved endogenous self-sustained timekeeping mechanisms to track
and anticipate cyclic changes in the environment. Circadian clocks, with a periodicity of …

Dental calculus as a tool to study the evolution of the mammalian oral microbiome

JC Brealey, HG Leitão, T van der Valk… - Molecular biology …, 2020 - academic.oup.com
Dental calculus, the calcified form of the mammalian oral microbial plaque biofilm, is a rich
source of oral microbiome, host, and dietary biomolecules and is well preserved in museum …