Alzheimer's disease (AD) and Parkinson's disease (PD) are the most common age-related
neurodegenerative disorders and hence pose remarkable socio-economical burdens to …

Natural biflavonoids, such as amentoflavone, bilobetin, ginkgetin, isoginkgetin,
taiwaniaflavone, morelloflavone, delicaflavone, hinokiflavone, and other derivatives (~ 40 …

The abnormal misfolding and aggregation of amyloid-β (Aβ) peptides into β-sheet enriched
insoluble deposits initiates a cascade of events leading to pathological processes and …

Alzheimer's disease (AD) is a progressive, chronic and severe neurodegenerative disorder
linked with cognitive and memory impairment that eventually lead to death. There are …

Abstract Background The accumulation of Amyloid β (Aβ) plays key roles in Alzheimer's
disease (AD) by inducing intracellular reactive oxygen species (ROS) and neuronal cell …

Over the past century, advances in biotechnology, biochemistry, and pharmacognosy have
spotlighted flavonoids, polyphenolic secondary metabolites that have the ability to modulate …

The search for natural plant-based products as new pharmacological alternatives to treat
various human pathologies has taken on great importance for researchers and research …

Recent advancements and growing attention about free radicals (ROS) and redox signaling
enable the scientific fraternity to consider their involvement in the pathophysiology of …

Cells generate unpaired electrons, typically via oxygen-or nitrogen-based by-products
during normal cellular respiration and under stressed situations. These pro-oxidant …

Biflavonoids, composed of two monoflavonoid residues, occur naturally in angiosperms,
bryophytes, ferns, and gymnosperms. More than 592 biflavonoids have been structurally …