Sarcopenia is a loss of muscle mass and function in the elderly that reduces mobility,
diminishes quality of life, and can lead to fall-related injuries, which require costly …

The neuromuscular junction (NMJ) is a specialized synapse that bridges the motor neuron
and the skeletal muscle fiber and is crucial for conversion of electrical impulses originating …

The absence of dystrophin in Duchenne muscular dystrophy disrupts the dystrophin-
associated glycoprotein complex resulting in skeletal muscle fiber fragility and atrophy …

Abstract An implanted neurotrophin-3 (NT3)-chitosan scaffold can recruit endogenous
neural stem cells to migrate to a lesion region and differentiate into mature neurons after …

The ability to form synapses is one of the fundamental properties required by the
mammalian nervous system to generate network connectivity. Structural and functional …

Background: Clinical use of platelet-rich plasma (PRP) and mesenchymal stem cells (MSCs)
has gained momentum as treatment for muscle injuries. Exosomes, or small cell–derived …

Schwann cells (SCs) at neuromuscular junctions (NMJs) play active roles in synaptic
homeostasis and repair. We have studied how SCs contribute to reinnervation of NMJs …

Duchenne muscular dystrophy (DMD) is a devastating neuromuscular disease in which
weakness, increased susceptibility to muscle injury, and inadequate repair appear to …

The neuromuscular junction (NMJ) is a specialized cholinergic synaptic interface between a
motor neuron and a skeletal muscle fiber that translates presynaptic electrical impulses into …

Pompe disease is a systemic metabolic disorder characterized by lack of acid-alpha
glucosidase (GAA) resulting in ubiquitous lysosomal glycogen accumulation. Respiratory …