Biological activity and pharmacological application of pectic polysaccharides: A review

ST Minzanova, VF Mironov, DM Arkhipova… - Polymers, 2018 - mdpi.com
Pectin is a polymer with a core of alternating α-1, 4-linked d-galacturonic acid and α-1, 2-l-
rhamnose units, as well as a variety of neutral sugars such as arabinose, galactose, and …

Neuroinflammation: a signature or a cause of epilepsy?

E Pracucci, V Pillai, D Lamers, R Parra… - International journal of …, 2021 - mdpi.com
Epilepsy can be both a primary pathology and a secondary effect of many neurological
conditions. Many papers show that neuroinflammation is a product of epilepsy, and that in …

Towards a treatment for neuroinflammation in epilepsy: interleukin-1 receptor antagonist, anakinra, as a potential treatment in intractable epilepsy

G Yamanaka, Y Ishida, K Kanou, S Suzuki… - International Journal of …, 2021 - mdpi.com
Febrile Infection-Related Epilepsy Syndrome (FIRES) is a unique catastrophic epilepsy
syndrome, and the development of drug-resistant epilepsy (DRE) is inevitable. Recently …

Neuroinflammation in post-traumatic epilepsy: pathophysiology and tractable therapeutic targets

R Sharma, WL Leung, A Zamani, TJ O'brien… - Brain sciences, 2019 - mdpi.com
Epilepsy is a common chronic consequence of traumatic brain injury (TBI), contributing to
increased morbidity and mortality for survivors. As post-traumatic epilepsy (PTE) is drug …

In search of antiepileptogenic treatments for post-traumatic epilepsy

PG Saletti, I Ali, PM Casillas-Espinosa, BD Semple… - Neurobiology of …, 2019 - Elsevier
Post-traumatic epilepsy (PTE) is diagnosed in 20% of individuals with acquired epilepsy,
and can impact significantly the quality of life due to the seizures and other functional or …

Saracatinib, a Src tyrosine kinase inhibitor, as a disease modifier in the rat DFP model: sex differences, Neurobehavior, gliosis, neurodegeneration, and nitro-oxidative …

M Gage, M Putra, L Wachter, K Dishman, M Gard… - Antioxidants, 2021 - mdpi.com
Diisopropylfluorophosphate (DFP), an organophosphate nerve agent (OPNA), exposure
causes status epilepticus (SE) and epileptogenesis. In this study, we tested the protective …

Epilepsy and innate immune system: a possible immunogenic predisposition and related therapeutic implications

N Matin, O Tabatabaie, R Falsaperla… - Human vaccines & …, 2015 - Taylor & Francis
Recent experimental studies and pathological analyses of patient brain tissue samples with
refractory epilepsy suggest that inflammatory processes and neuroinflammation plays a key …

Intracerebroventricular injection of propionic acid, an enteric metabolite implicated in autism, induces social abnormalities that do not differ between seizure-prone …

SR Shultz, NAB Aziz, L Yang, M Sun… - Behavioural brain …, 2015 - Elsevier
Autism is a complex neurodevelopmental disorder that is characterized by social
abnormalities. Genetic, dietary and gut-related factors are implicated in autism, however the …

[HTML][HTML] Structural characterization of polysaccharides from Cabernet Franc, Cabernet Sauvignon and Sauvignon Blanc wines: Anti-inflammatory activity in LPS …

I de Lacerda Bezerra, ARC Caillot, LCGF Palhares… - Carbohydrate …, 2018 - Elsevier
The structural characterization of the polysaccharides and in vitro anti-inflammatory
properties of Cabernet Franc (WCF), Cabernet Sauvignon (WCS) and Sauvignon Blanc …

Blockade of Kv1. 3 potassium channel inhibits microglia-mediated neuroinflammation in epilepsy

X Zhang, P Liang, Y Zhang, Y Wu, Y Song… - International Journal of …, 2022 - mdpi.com
Epilepsy is a chronic neurological disorder whose pathophysiology relates to inflammation.
The potassium channel Kv1. 3 in microglia has been reported as a promising therapeutic …