Evolving therapies for myocardial ischemia/reperfusion injury

B Ibáñez, G Heusch, M Ovize, F Van de Werf - Journal of the American …, 2015 - jacc.org
The damage inflicted on the myocardium during acute myocardial infarction is the result of 2
processes: ischemia and subsequent reperfusion (ischemia/reperfusion injury). During the …

Coronary microvascular obstruction in acute myocardial infarction

G Niccoli, G Scalone, A Lerman… - European heart …, 2016 - academic.oup.com
The success of a primary percutaneous intervention (PCI) in the setting of ST elevation
myocardial infarction depends on the functional and structural integrity of coronary …

2013 ACCF/AHA guideline for the management of ST-elevation myocardial infarction: a report of the American College of Cardiology Foundation/American Heart …

PT O'Gara, FG Kushner, DD Ascheim, DE Casey… - Journal of the American …, 2013 - jacc.org
1.1. Methodology and Evidence Review The recommendations listed in this document are,
whenever possible, evidence based. The current document constitutes a full revision and …

Optimized treatment of ST-elevation myocardial infarction: the unmet need to target coronary microvascular obstruction as primary treatment goal to further improve …

G Niccoli, RA Montone, B Ibanez, H Thiele… - Circulation …, 2019 - Am Heart Assoc
Primary percutaneous coronary intervention is nowadays the preferred reperfusion strategy
for patients with acute ST-segment–elevation myocardial infarction, aiming at restoring …

Coronary microvascular dysfunction: mechanisms and functional assessment

PG Camici, G d'Amati, O Rimoldi - Nature Reviews Cardiology, 2015 - nature.com
Obstructive disease of the epicardial coronary arteries was recognized as the cause of
angina pectoris> 2 centuries ago, and sudden thrombotic occlusion of an epicardial …

Comprehensive prognosis assessment by CMR imaging after ST-segment elevation myocardial infarction

I Eitel, S De Waha, J Wöhrle, G Fuernau, P Lurz… - Journal of the American …, 2014 - jacc.org
Background: Although the prognostic value of findings from cardiac magnetic resonance
(CMR) imaging has been established in single-center center studies in patients with ST …

Heart–gut microbiota communication determines the severity of cardiac injury after myocardial ischaemia/reperfusion

J Zhao, Q Zhang, W Cheng, Q Dai, Z Wei… - Cardiovascular …, 2023 - academic.oup.com
Aims Recent studies have suggested a key role of intestinal microbiota in pathological
progress of multiple organs via immune modulation. However, the interactions between …

Automated diagnosis of cardiovascular diseases from cardiac magnetic resonance imaging using deep learning models: A review

M Jafari, A Shoeibi, M Khodatars, N Ghassemi… - Computers in Biology …, 2023 - Elsevier
In recent years, cardiovascular diseases (CVDs) have become one of the leading causes of
mortality globally. At early stages, CVDs appear with minor symptoms and progressively get …

Angiogenesis in the infarcted myocardium

C Cochain, KM Channon, JS Silvestre - Antioxidants & redox …, 2013 - liebertpub.com
Significance: Proangiogenic therapy appeared a promising strategy for the treatment of
patients with acute myocardial infarction (MI), as de novo formation of microvessels, has the …

Colchicine inhibits neutrophil extracellular trap formation in patients with acute coronary syndrome after percutaneous coronary intervention

K Vaidya, B Tucker, R Kurup, C Khandkar… - Journal of the …, 2021 - Am Heart Assoc
Background Release of neutrophil extracellular traps (NETs) after percutaneous coronary
intervention (PCI) in acute coronary syndrome (ACS) is associated with periprocedural …