How virulence evolves after a virus jumps to a new host species is central to disease
emergence. Our current understanding of virulence evolution is based on insights drawn …

The study of virus disease emergence, whether it can be predicted and how it might be
prevented, has become a major research topic in biomedicine. Here we show that efforts to …

The cross-species transmission of viruses from one host species to another is responsible
for the majority of emerging infections. However, it is unclear whether some virus families …

Viruses are submicroscopic, obligate intracellular parasites that carry either DNA or RNA as
their genome, protected by a capsid. Viruses are genetic entities that propagate by using the …

Hepatitis viruses are major threats to human health. During the last decade, highly diverse
viruses related to human hepatitis viruses were found in animals other than primates …

Background Three flaviviruses (equine pegivirus [EPgV]; Theiler's disease–associated virus
[TDAV]; non‐primate hepacivirus [NPHV]) and equine parvovirus (EqPV‐H) are present in …

Horses and other equids can be infected with several viruses of the family Flaviviridae,
belonging to the genus Flavivirus and Hepacivirus. This consensus statement focuses on …

Equine parvovirus hepatitis (EqPV‐H) was first described in 2018 in a fatal case of Theiler's
disease which followed the administration of an equine‐origin biological product. The virus …

Preclinical testing of novel therapeutics for chronic hepatitis B (CHB) requires suitable
animal models. Equids host homologs of hepatitis C virus (HCV). Because coinfections of …

Since its first discovery by Arnold Theiler in 1918, serum hepatitis also known as Theiler's
disease has been reported worldwide, causing idiopathic acute hepatitis and liver failure in …