Immunoglobulin A nephropathy (IgAN) is the most common primary glomerulonephritis
worldwide. It is a leading cause of chronic kidney disease and progresses to end-stage …

IgA nephropathy (IgAN) is a leading cause of CKD and renal failure. Recent international
collaborative efforts have led to important discoveries that have improved our understanding …

Importance The effect of glucocorticoids on major kidney outcomes and adverse events in
IgA nephropathy has been uncertain. Objective To evaluate the efficacy and adverse effects …

The Kidney Disease: Improving Global Outcomes (KDIGO) initiative organized a
Controversies Conference on glomerular diseases in November 2017. The conference …

Abstract Globally, IgA nephropathy (IgAN) is the most common primary glomerulonephritis
that can progress to renal failure. The exact pathogenesis of IgAN is not well defined, but …

The precise pathogenesis of immunoglobulin A nephropathy (IgAN) is still not clearly
established but emerging evidence confirms a pivotal role for mucosal immunity. This review …

Introduction Narsoplimab is a human monoclonal antibody against mannan-associated
lectin-binding serine protease− 2 (MASP-2). Now in a phase 3 study, narsoplimab was …

Immunoglobulin A (IgA) is the most abundant isotype of antibodies, provides a first line of
defense at mucosal surfaces against pathogens, and thereby contributes to mucosal …

IgA nephropathy (IgAN) is the most common form of primary glomerulonephritis worldwide
and a common cause of end-stage renal disease. Evaluation of a kidney biopsy is …

IgA nephropathy (IgAN) is common and often progresses to end stage renal disease. IgAN
encompasses a wide range of histology and clinical features. IgAN pathogenesis is …