Oxidative stress and the ageing endocrine system

G Vitale, S Salvioli, C Franceschi - Nature Reviews Endocrinology, 2013 - nature.com
Ageing is a process characterized by a progressive decline in cellular function, organismal
fitness and increased risk of age-related diseases and death. Several hundred theories …

Mechanisms in endocrinology: aging and anti-aging: a combo-endocrinology overview

E Diamanti-Kandarakis, M Dattilo… - European journal of …, 2017 - academic.oup.com
Aging and its underlying pathophysiological background has always attracted the attention
of the scientific society. Defined as the gradual, time-dependent, heterogeneous decline of …

Inflammatory stimuli induce inhibitory S-nitrosylation of the deacetylase SIRT1 to increase acetylation and activation of p53 and p65

S Shinozaki, K Chang, M Sakai, N Shimizu… - Science …, 2014 - science.org
Inflammation increases the abundance of inducible nitric oxide synthase (iNOS), leading to
enhanced production of nitric oxide (NO), which can modify proteins by S-nitrosylation …

[HTML][HTML] Aging, metabolic syndrome and the heart

G Veronica, RRM Esther - Aging and disease, 2012 - ncbi.nlm.nih.gov
Aging is accelerated when metabolic and cardiovascular diseases (CVD) are present and
the risk of these diseases increases with age. Many predisposing conditions which increase …

Bergamot essential oil attenuate aluminum-induced anxiety-like behavior through antioxidation, anti-inflammatory and GABA regulation in rats

Y Cui, Y Che, H Wang - Food and Chemical Toxicology, 2020 - Elsevier
A large number of studies showed that aluminum (Al) has potential neurotoxicity to human
and animal bodies. Al-treated animals showed anxiety-like behavior, oxidative stress …

Obesity and aging: determinants of endothelial cell dysfunction and atherosclerosis

M Barton - Pflügers Archiv-European Journal of Physiology, 2010 - Springer
Endothelial cells are both the source and target of factors contributing to atherosclerosis.
After the discovery of the endothelium-derived relaxing factor (EDRF) by Robert F. Furchgott …

[HTML][HTML] Monoaminergic and histaminergic strategies and treatments in brain diseases

G Di Giovanni, D Svob Strac, M Sole… - Frontiers in …, 2016 - frontiersin.org
The monoaminergic systems are the target of several drugs for the treatment of mood, motor
and cognitive disorders as well as neurological conditions. In most cases, advances have …

Chrysanthemum indicum Linné extract inhibits the inflammatory response by suppressing NF-κB and MAPKs activation in lipopolysaccharide-induced RAW 264.7 …

MS Cheon, T Yoon, G Choi, BC Moon, AY Lee… - Journal of …, 2009 - Elsevier
AIMS OF STUDY: Although the flowers of Chrysanthemum indicum Linné (Asteraceae) have
long been used in traditional Korean and Chinese medicine to treat inflammatory diseases …

A critical review of radiotracers in the positron emission tomography imaging of traumatic brain injury: FDG, tau, and amyloid imaging in mild traumatic brain injury and …

C Ayubcha, ME Revheim, A Newberg… - European Journal of …, 2021 - Springer
Purpose Positron emission tomography (PET) has been widely utilized in the study of
traumatic brain injury (TBI) for decades. While most applications of PET have attempted to …

Central Apelin Controls Glucose Homeostasis via a Nitric Oxide-Dependent Pathway in Mice

T Duparc, A Colom, PD Cani, N Massaly… - Antioxidants & redox …, 2011 - liebertpub.com
Aims: Apelin and its receptor have emerged as promising targets for the treatment of insulin
resistance. Indeed, peripheral administration of apelin stimulates glucose utilization and …