The expanding role of pyridine and dihydropyridine scaffolds in drug design
Y Ling, ZY Hao, D Liang, CL Zhang… - Drug design …, 2021 - Taylor & Francis
Pyridine-based ring systems are one of the most extensively used heterocycles in the field of
drug design, primarily due to their profound effect on pharmacological activity, which has led …
drug design, primarily due to their profound effect on pharmacological activity, which has led …
[HTML][HTML] Heterocyclic anticancer compounds: recent advances and the paradigm shift towards the use of nanomedicine's tool box
The majority of heterocycle compounds and typically common heterocycle fragments
present in most pharmaceuticals currently marketed, alongside with their intrinsic versatility …
present in most pharmaceuticals currently marketed, alongside with their intrinsic versatility …
[HTML][HTML] Pyridine compounds with antimicrobial and antiviral activities
M Marinescu, CV Popa - International journal of molecular sciences, 2022 - mdpi.com
In the context of the new life-threatening COVID-19 pandemic caused by the SARS-CoV-2
virus, finding new antiviral and antimicrobial compounds is a priority in current research …
virus, finding new antiviral and antimicrobial compounds is a priority in current research …
Insights into the structure activity relationship of nitrogen-containing heterocyclics for the development of antidepressant compounds: An updated review
Abstract According to the World Health Organization (WHO), depression is a common
mental disorder and includes complex interaction between social and psychological …
mental disorder and includes complex interaction between social and psychological …
[PDF][PDF] A review on heterocyclic: Synthesis and their application in medicinal chemistry of imidazole moiety
M Hossain, AK Nanda - Science, 2018 - researchgate.net
In an organic chemistry, largest families of organic compounds are belongs in the
heterocyclic compounds. In our daily life important of heterocyclic compounds are of very …
heterocyclic compounds. In our daily life important of heterocyclic compounds are of very …
Antiviral activities of pyridine fused and pyridine containing heterocycles, a review (from 2000 to 2020)
SR Alizadeh, MA Ebrahimzadeh - Mini Reviews in Medicinal …, 2021 - ingentaconnect.com
Heterocyclic compounds play a critical role in medicinal chemistry, and many available
drugs contain heterocyclic rings. A six-membered heterocyclic compound, pyridine, showed …
drugs contain heterocyclic rings. A six-membered heterocyclic compound, pyridine, showed …
A therapeutic journey of pyridine-based heterocyclic compounds as potent anticancer agents: a review (from 2017 to 2021)
M Alrooqi, S Khan, FA Alhumaydhi… - Anti-Cancer Agents …, 2022 - ingentaconnect.com
Pyridine derivatives are the most common and significant heterocyclic compounds, which
show their fundamental characteristics to various pharmaceutical agents and natural …
show their fundamental characteristics to various pharmaceutical agents and natural …
Dependence on linkers' flexibility designed for benzenesulfonamides targeting discovery of novel hCA IX inhibitors as potent anticancer agents
Herein we reported the design and synthesis of two series comprising twenty-two
benzenesulfonamides that integrate the s-triazine moiety. Target compounds successfully …
benzenesulfonamides that integrate the s-triazine moiety. Target compounds successfully …
A review on synthesis, reactions and biological properties of seven membered heterocyclic compounds: azepine, azepane, azepinone
M Kaur, S Garg, DS Malhi… - Current Organic Chemistry, 2021 - ingentaconnect.com
Seven membered heterocyclic Azepine and its derivatives have great pharmacological and
therapeutic implications. In this review, the literature of the last fifty years has been exploited …
therapeutic implications. In this review, the literature of the last fifty years has been exploited …
Investigation of biological activity of 2, 3-disubstituted quinazolin-4 (1 H)-ones against Mycobacterium tuberculosis and DNA via docking, spectroscopy and DFT …
A series of 2, 3-disubstituted quinazolin-4 (1H)-ones (3a–j) were screened for their
antimicrobial activity via the minimum inhibitory concentration method (MIC). The in vitro anti …
antimicrobial activity via the minimum inhibitory concentration method (MIC). The in vitro anti …