Imaging and biophysical modelling of thrombogenic mechanisms in atrial fibrillation and stroke
A Qureshi, GYH Lip, DA Nordsletten… - Frontiers in …, 2023 - frontiersin.org
Atrial fibrillation (AF) underlies almost one third of all ischaemic strokes, with the left atrial
appendage (LAA) identified as the primary thromboembolic source. Current stroke risk …
appendage (LAA) identified as the primary thromboembolic source. Current stroke risk …
Computational flow dynamic analysis in left atrial appendage thrombus formation risk: A review
S Valvez, M Oliveira-Santos, AP Piedade… - Applied Sciences, 2023 - mdpi.com
Atrial fibrillation (AF) is a common cardiac arrhythmia characterized by irregular and rapid
electrical activity in the atria, leading to ineffective contraction and poor blood flow. More …
electrical activity in the atria, leading to ineffective contraction and poor blood flow. More …
Hemodynamics of the heart's left atrium based on a variational multiscale-LES numerical method
In this paper, we investigate the haemodynamics of a left atrium (LA) by proposing a
computational model suitable to provide physically meaningful fluid dynamics indications …
computational model suitable to provide physically meaningful fluid dynamics indications …
Impact of atrial fibrillation on left atrium haemodynamics: A computational fluid dynamics study
We analyse the haemodynamics of the left atrium, highlighting differences between healthy
individuals and patients affected by atrial fibrillation. The computational study is based on …
individuals and patients affected by atrial fibrillation. The computational study is based on …
[HTML][HTML] An electromechanics-driven fluid dynamics model for the simulation of the whole human heart
We introduce a multiphysics and geometric multiscale computational model, suitable to
describe the hemodynamics of the whole human heart, driven by a four-chamber …
describe the hemodynamics of the whole human heart, driven by a four-chamber …
Sensitivity analysis of in silico fluid simulations to predict thrombus formation after left atrial appendage occlusion
J Mill, V Agudelo, AL Olivares, MI Pons, E Silva… - Mathematics, 2021 - mdpi.com
Atrial fibrillation (AF) is nowadays the most common human arrhythmia and it is considered
a marker of an increased risk of embolic stroke. It is known that 99% of AF-related thrombi …
a marker of an increased risk of embolic stroke. It is known that 99% of AF-related thrombi …
The role of the pulmonary veins on left atrial flow patterns and thrombus formation
Atrial fibrillation (AF) is the most common human arrhythmia, forming thrombi mostly in the
left atrial appendage (LAA). However, the relation between LAA morphology, blood patterns …
left atrial appendage (LAA). However, the relation between LAA morphology, blood patterns …
Regional left atrial conduction velocity in the anterior wall is associated with clinical recurrence of atrial fibrillation after catheter ablation: efficacy in combination with …
S Ohguchi, Y Inden, S Yanagisawa, R Fujita… - BMC Cardiovascular …, 2022 - Springer
Background Left atrial (LA) conduction velocity (CV) is an electrical remodeling parameter of
atrial fibrillation (AF) substrate. However, the pathophysiological substrate of LA-CV and its …
atrial fibrillation (AF) substrate. However, the pathophysiological substrate of LA-CV and its …
On the impact of left upper lobectomy on the left atrial hemodynamics
T Otani, T Yoshida, W Yi, S Endo, S Wada - Frontiers in Physiology, 2022 - frontiersin.org
The left atrium (LA) functions to transport oxygenated blood from the pulmonary veins (PVs)
to the left ventricle (LV). LA hemodynamics has received much attention because thrombosis …
to the left ventricle (LV). LA hemodynamics has received much attention because thrombosis …
Modelling left atrial flow and blood coagulation for risk of thrombus formation in atrial fibrillation
Atrial fibrillation (AF) diminishes left atrial (LA) mechanical function and impairs blood flow.
The latter can lead to blood stasis and increased risk of thrombus formation and stroke. We …
The latter can lead to blood stasis and increased risk of thrombus formation and stroke. We …