The regulation of body temperature is one of the most critical functions of the nervous
system. Here we review our current understanding of thermoregulation in mammals. We …

Buildings could actively participate in the emerging smart electrical grid if they were able to
incorporate dynamic modulations of indoor temperature set-points. But the mechanisms of …

The nervous system uses various coding strategies to process sensory inputs. For example,
the olfactory system uses large receptor repertoires and is wired to recognize diverse …

Humans detect skin temperature changes that are perceived as warm or cool. Like humans,
mice report forepaw skin warming with perceptual thresholds of less than 1° C and do not …

Temperature is a universal cue and regulates many essential processes ranging from
enzymatic reactions to species migration. Due to the profound impact of temperature on …

Understanding complex biological systems requires visualizing structures and processes
deep within living organisms. We developed a compact adaptive optics module and …

Dorsal root ganglia (DRG) somatosensory neurons detect mechanical, thermal, and
chemical stimuli acting on the body. Achieving a holistic view of how different DRG neuron …

Maintenance of mammalian core body temperature within a narrow range is a fundamental
homeostatic process to optimize cellular and tissue function, and to improve survival in …

As endotherms, humans exposed to a compensable cold environment rely on an increase in
thermogenic rate to counteract heat lost to the environment, thereby maintaining a stable …

Temperature is a fundamental sensory modality separate from touch, with dedicated
receptor channels and primary afferent neurons for cool and warm,–. Unlike for other …