[HTML][HTML] Mechanisms of circRNA/lncRNA-miRNA interactions and applications in disease and drug research

B Ma, S Wang, W Wu, P Shan, Y Chen, J Meng… - Biomedicine & …, 2023 - Elsevier
In recent years, breakthroughs in bioinformatics have been made with the discovery of many
functionally significant non-coding RNAs (ncRNAs). The discovery of these ncRNAs has …

Updated review of advances in microRNAs and complex diseases: experimental results, databases, webservers and data fusion

L Huang, L Zhang, X Chen - Briefings in bioinformatics, 2022 - academic.oup.com
MicroRNAs (miRNAs) are gene regulators involved in the pathogenesis of complex
diseases such as cancers, and thus serve as potential diagnostic markers and therapeutic …

Recent progress in miRNA biogenesis and decay

X Bofill-De Ros, UA Vang Ørom - RNA biology, 2024 - Taylor & Francis
MicroRNAs are a class of small regulatory RNAs that mediate regulation of protein synthesis
by recognizing sequence elements in mRNAs. MicroRNAs are processed through a series …

MicroRNAs in drug addiction: Current status and future perspectives

Y Zhao, F Qin, S Han, S Li, Y Zhao, H Wang… - Pharmacology & …, 2022 - Elsevier
Drug addiction is a chronic and relapsing brain disorder characterized by compulsive drug
seeking and continued drug use despite adverse consequences. The high prevalence and …

Post‐transcriptional regulation of polycistronic microRNAs

M Vilimova, S Pfeffer - Wiley Interdisciplinary Reviews: RNA, 2023 - Wiley Online Library
An important proportion of microRNA (miRNA) genes tend to lie close to each other within
animal genomes. Such genomic organization is generally referred to as miRNA clusters …

[HTML][HTML] Bioinformatic tools for the analysis and prediction of ncRNA interactions

A Rincón-Riveros, D Morales, JA Rodríguez… - International Journal of …, 2021 - mdpi.com
Noncoding RNAs (ncRNAs) play prominent roles in the regulation of gene expression via
their interactions with other biological molecules such as proteins and nucleic acids …

Circulating microRNAs as cancer biomarkers in liquid biopsies

B Suárez, C Solé, M Márquez, F Nanetti… - Systems Biology of …, 2022 - Springer
Biological fluids such as blood, saliva, and urine offer a rich source of biomarkers that have
the potential to change the paradigm of cancer management. By allowing routine …

[HTML][HTML] Machine learning in the development of targeting microRNAs in human disease

Y Luo, L Peng, W Shan, M Sun, L Luo, W Liang - Frontiers in Genetics, 2023 - frontiersin.org
A microRNA is a small, single-stranded, non-coding ribonucleic acid that plays a crucial role
in RNA silencing and can regulate gene expression. With the in-depth study of miRNA in …

An integrated workflow for biomarker development using microRNAs in extracellular vesicles for cancer precision medicine

Y Chen, T Wu, Z Zhu, H Huang, L Zhang, A Goel… - Seminars in Cancer …, 2021 - Elsevier
EV-miRNAs are microRNA (miRNA) molecules encapsulated in extracellular vesicles (EVs),
which play crucial roles in tumor pathogenesis, progression, and metastasis. Recent studies …

[HTML][HTML] Non-coding RNA crosstalk with nuclear receptors in liver disease

J Wu, LE Nagy, S Liangpunsakul, L Wang - Biochimica et Biophysica Acta …, 2021 - Elsevier
The dysregulation of nuclear receptors (NRs) underlies the pathogenesis of a variety of liver
disorders. Non-coding RNAs (ncRNAs) are defined as RNA molecules transcribed from …