Extensive research has found strongly increased generation of reactive oxygen species, free
radicals, and reactive nitrogen species during acute physical exercise that can lead to …

Nutrients | Free Full-Text | Is Melatonin the “Next Vitamin D”?: A Review of
Emerging Science, Clinical Uses, Safety, and Dietary Supplements Next Article in Journal …

Melatonin modulates a wide range of physiological functions with pleiotropic effects on the
immune system. Despite the large number of reports implicating melatonin as an …

Antioxidant supplements are commonly consumed by endurance athletes to minimize
exercise-induced oxidative stress, with the intention of enhancing recovery and improving …

Free radicals generated within subcellular compartments damage macromolecules which
lead to severe structural changes and functional alterations of cellular organelles. A …

Melatonin is a highly evolutionary conserved endogenous molecule that is mainly produced
by the pineal gland, but also by other nonendocrine organs, of most mammals including …

Aims Lipopolysaccharide (LPS) induces oxidative stress and neuroinflammation both in vivo
and in vitro. Here, we provided the first detailed description of the mechanism of melatonin …

Melatonin possesses the indoleamine structure and exerts antioxidant and anti-inflammatory
actions and other physiological properties. Physical exercise can influence secretion of …

Chronic inflammation contributes to multiple diseases including cardiovascular diseases,
autoimmune disorders, metabolic disorders, and psychiatric conditions. Melatonin, a …

Introduction The stress response is different in various individuals, however, the
mechanisms that could explain these distinct effects are not well known and the molecular …