Spatial metabolomics is an emerging field of omics research that has enabled localizing
metabolites, lipids, and drugs in tissue sections, a feat considered impossible just two …

Desorption electrospray ionization mass spectrometry imaging (DESI‐MSI) is one of the
least specimen destructive ambient ionization mass spectrometry tissue imaging methods. It …

Significant advances in mass spectrometry imaging (MSI) have pushed the boundaries in
obtaining spatial information and quantification in biological samples. Quantitative MSI …

The genomic landscape of colorectal cancer (CRC) is shaped by inactivating mutations in
tumour suppressors such as APC, and oncogenic mutations such as mutant KRAS. Here we …

A new tissue sample embedding and processing method is presented that provides
downstream compatibility with numerous different histological, molecular biology, and …

Current gaps in drug safety sciences can result from the inability (1) to identify hazard across
multiple target organs,(2) to predict and risk assess with certainty against drug safety …

During the past decade, mass spectrometry imaging (MSI) has become a robust and
versatile methodology to support modern pharmaceutical research and development. The …

Mass spectrometry imaging (MSI) is an established analytical tool capable of defining and
understanding complex tissues by determining the spatial distribution of biological …

Mass spectrometry imaging (MSI) provides insight into the molecular distribution of a broad
range of compounds and, therefore, is frequently applied in the pharmaceutical industry …

The brain is the most advanced organ with various complex structural and functional
microregions. It is often challenging to understand what and where the molecular events …