[HTML][HTML] Pattern recognition receptors in health and diseases

D Li, M Wu - Signal transduction and targeted therapy, 2021 - nature.com
Pattern recognition receptors (PRRs) are a class of receptors that can directly recognize the
specific molecular structures on the surface of pathogens, apoptotic host cells, and damaged …

[HTML][HTML] Signaling pathways in rheumatoid arthritis: implications for targeted therapy

Q Ding, W Hu, R Wang, Q Yang, M Zhu, M Li… - Signal transduction and …, 2023 - nature.com
Rheumatoid arthritis (RA) is an incurable systemic autoimmune disease. Disease
progression leads to joint deformity and associated loss of function, which significantly …

[HTML][HTML] Anti-inflammatory microRNAs and their potential for inflammatory diseases treatment

A Tahamtan, M Teymoori-Rad, B Nakstad… - Frontiers in …, 2018 - frontiersin.org
Inflammation is a complicated biological and pathophysiological cascade of responses to
infections and injuries, and inflammatory mechanisms are closely related to many diseases …

MicroRNAs in rheumatoid arthritis: From pathogenesis to clinical impact

G Evangelatos, GE Fragoulis, V Koulouri… - Autoimmunity reviews, 2019 - Elsevier
Over the last decade, many epigenetic mechanisms that contribute in the pathogenesis of
autoimmune disorders have been revealed. MicroRNAs (miRNAs) are small, non-coding …

[HTML][HTML] Role of host and pathogen-derived microRNAs in immune regulation during infectious and inflammatory diseases

K Chandan, M Gupta, M Sarwat - Frontiers in immunology, 2020 - frontiersin.org
MicroRNAs (miRNAs, miRs) are short, endogenously initiated, non-coding RNAs that bind to
target mRNAs, leading to the degradation or translational suppression of respective mRNAs …

Stigmasterol protects rats from collagen induced arthritis by inhibiting proinflammatory cytokines

MA Khan, AHMG Sarwar, R Rahat, RS Ahmed… - International …, 2020 - Elsevier
Rheumatoid arthritis (RA) is an autoimmune disorder, in which imbalance in synthesis and
production of inflammatory cytokines promotes cartilage and bone destruction. Out of the …

[HTML][HTML] Epigenetic changes in the pathogenesis of rheumatoid arthritis

MV Nemtsova, DV Zaletaev, IV Bure… - Frontiers in …, 2019 - frontiersin.org
Rheumatoid arthritis (RA) is a systemic autoimmune disease that affects about 1% of the
world's population. The etiology of RA remains unknown. It is considered to occur in the …

A guide to miRNAs in inflammation and innate immune responses

C Nejad, HJ Stunden, MP Gantier - The FEBS journal, 2018 - Wiley Online Library
The discovery of micro RNA s (miRNAs) in the early 1990's has revolutionized our thinking
of post‐transcriptional gene control. miRNAs are involved in the regulation of almost every …

[HTML][HTML] The role of microRNAs in inflammation

K Das, LVM Rao - International Journal of Molecular Sciences, 2022 - mdpi.com
Inflammation is a biological response of the immune system to various insults, such as
pathogens, toxic compounds, damaged cells, and radiation. The complex network of pro …

Dysregulation of microRNAs in autoimmune diseases: Pathogenesis, biomarkers and potential therapeutic targets

H Long, X Wang, Y Chen, L Wang, M Zhao, Q Lu - Cancer letters, 2018 - Elsevier
MicroRNAs (miRNAs) are small, single-stranded, endogenous non-coding RNAs that
repress the expression of target genes via post-transcriptional mechanisms. Due to their …