Plant-derived bioactive compounds in the management of neurodegenerative disorders: Challenges, future directions and molecular mechanisms involved in …

S Shoaib, MA Ansari, AA Fatease, AY Safhi, U Hani… - Pharmaceutics, 2023 - mdpi.com
Neurodegenerative disorders encompass a wide range of pathological conditions caused
by progressive damage to the neuronal cells and nervous-system connections, which …

Genus Sophora: a comprehensive review on secondary chemical metabolites and their biological aspects from past achievements to future perspectives

HI Abd-Alla, D Souguir, MO Radwan - Archives of pharmacal research, 2021 - Springer
Sophora is deemed as one of the most remarkable genera of Fabaceae, and the third
largest family of flowering plants. The genus Sophora comprises approximately 52 species …

GC/MS Analysis of Essential Oil and Enzyme Inhibitory Activities of Syzygium cumini (Pamposia) Grown in Egypt: Chemical Characterization and Molecular Docking …

HAS El-Nashar, WM Eldehna, ST Al-Rashood… - Molecules, 2021 - mdpi.com
Syzygium cumini (Pomposia) is a well-known aromatic plant belonging to the family
Myrtaceae, and has been reported for its various traditional and pharmacological potentials …

Chemical Constituents, Antioxidant, and Enzyme Inhibitory Activities Supported by In-Silico Study of n-Hexane Extract and Essential Oil of Guava Leaves

SH Aly, OA Eldahshan, ST Al-Rashood, FA Binjubair… - Molecules, 2022 - mdpi.com
Psidium guajava (Guava tree) is one of the most widely known species in the family
Myrtaceae. The Guava tree has been reported for its potential antioxidant, anti-inflammatory …

Insights on benzodiazepines' potential in Alzheimer's disease

HM Al-Kuraishy, AI Al-Gareeb, AA Alsayegh… - Life Sciences, 2023 - Elsevier
Alzheimer's disease (AD) is the most frequent type of dementia characterized by the
deposition of amyloid beta (Aβ) plaque and tau-neurofibrillary tangles (TNTs) in the brain …

Formononetin improves cardiac function and depressive behaviours in myocardial infarction with depression by targeting GSK-3β to regulate macrophage/microglial …

Y Yang, T Huang, H Zhang, X Li, S Shi, X Tian… - Phytomedicine, 2023 - Elsevier
Background Depression is a common complication after myocardial infarction (MI) that can
seriously affect the prognosis of MI. Purpose To investigate whether formononetin could …

Electrospun Tamarindus indica-loaded antimicrobial PMMA/cellulose acetate/PEO nanofibrous scaffolds for accelerated wound healing: in-vitro and in-vivo …

SS Goher, SH Aly, MM Abu-Serie… - International Journal of …, 2024 - Elsevier
In this work, Tamarindus indica (T. indica)-loaded crosslinked poly (methyl
methacrylate)(PMMA)/cellulose acetate (CA)/poly (ethylene oxide)(PEO) electrospun …

Comparative Metabolic Study of Tamarindus indica L.'s Various Organs Based on GC/MS Analysis, In Silico and In Vitro Anti-Inflammatory and Wound Healing …

SH Aly, MA El-Hassab, SS Elhady, HA Gad - Plants, 2022 - mdpi.com
The chemical composition of the n-hexane extract of Tamarindus indica's various organs—
bark, leaves, seeds, and fruits (TIB, TIL, TIS, TIF)—was investigated using gas …

Phytochemical Investigation of Three Cystoseira Species and Their Larvicidal Activity Supported with In Silico Studies

SH Aly, AM Elissawy, D Salah, NA Alfuhaid, OH Zyaan… - Marine Drugs, 2023 - mdpi.com
Culex pipiens mosquitoes are transmitters of many viruses and are associated with the
transmission of many diseases, such as filariasis and avian malaria, that have a high rate of …

Focusing on formononetin: recent perspectives for its neuroprotective potentials

J Tian, XQ Wang, Z Tian - Frontiers in Pharmacology, 2022 - frontiersin.org
Nervous system is the most complex system of the human body, hence, the neurological
diseases often lack effective treatment strategies. Natural products have the potential to yield …