… Onset of T cell exhaustion is caused by a high load of antigen and amplified levels of anti-
and pro-inflammatory cytokines, characteristic of the host septic environment. A recent study …

… IL-1 family cytokines is considered an early marker of sepsis, and the cytokines can serve as
… The present review aims to provide an overview of IL-1 family cytokines in sepsis and their …

… Cytokines Overall, cytokine profiles can be useful to assess severity and mortality in sepsis
patients, … Cytokines Overall, cytokine profiles can be useful to assess severity and mortality in …

… Association between cytokine levels and sepsis type … serum cytokine levels and the early-
or late-onset type of sepsis, … early-onset sepsis (196 pg/mL) and for late-onset sepsis (109.7 pg/…

… Cytokines play a pivotal role in the progression of the sepsis response. In early sepsis
TNF-α, a pro-inflammatory cytokine … , is a marker of early sepsis and enhances the adaptive …

… 19 and compared the cytokine profiles with those from ARDS and sepsis patients … cytokine
storm” cytokines, we also performed a more exploratory analysis of the additional 70 cytokines …

… of proinflammatory cytokines, … of cytokines and found IL-1β, IL-6, IL-8, MCP-1, IL-10, and
plasminogen activator inhibitor 1 (PAI-1) levels were increased in the acute phase of sepsis in …

… now that acute systemic challenge models have little relevance for human sepsis, uncontrolled
activity of proinflammatory cytokines still is considered to contribute to injury in sepsis. …

… in patients with severe sepsis and linked to mortality as compared to patients with … sepsis
[212]. A smaller study comparing 16 septic shock patients with 11 shock patients without sepsis …

… of NF-κB, further increasing cytokine production. Although immune cells are responsible for
most cytokine production during sepsis, ECs are not only the target of cytokines, but are also, …