… lung carcinoma; other risks include genetic factors and exposure to radon gas, asbestos,
secondhand smoke, and air pollution. Nicotine, … 5 nicotinic acetylcholine receptor subunit gene …

… susceptibility to lung cancer development. Furthermore, the gene cluster encoding the α5,
α3, and β4 nAChR subunits plays … PKC/IP3 signaling as well as the MAP/ERK, p38, and JNK …

… We included all human based studies on GWAS for lung cancer which … of Genes and
Genome (KEGG) shows that these receptors were found to be overexpressed where nicotine, 4-(…

… were involved in the progression of lung cancer [49]. Altogether, … and invited cartographers
to complete the map in order to … Evaluation of nicotinic acetylcholine receptor (nAChR) …

… gene cluster variants rs16969968 and rs578776 of nicotinic … diverse neuronal nicotinic
acetylcholine receptors (nAChRs), … identifies a susceptibility locus for lung cancer at 15q25.1. …

… small molecules for lung cancer treatment. Nicotinic acetylcholine receptors (nAChRs) have
… The CHRNA7 gene, which encodes the α7 subunit, is increased in patients with SCLC who …

… nicotinic acetylcholinereceptor alpha 5 subunit (CHRNA5) gene locus on chromosome
15q25 and lung cancer… on the activity of the nicotinic acetylcholine receptor found in both the …

… This suggests the effect of nicotine, from ECS, might be directly carcinogenic. We provide …
the nicotinic acetylcholine receptor (nAChR), consistently linked to lung cancer in large genetic …

… the activation of nicotinic acetylcholine receptors (nAChRs). … in the lung cancer cell line
A549 and the breast cancer line … (A) Heat map view of several nicotinic acetylcholine receptor …

… neurotransmitter acetylcholine (ACh), and the α5-nicotinic acetylcholine … Paraffin sections
of BALB/c nude mouse lung tumour xenografts were … α5-Nicotinic acetylcholine receptor …