Exposure to air pollutants has been previously associated with respiratory viral infections,
including influenza, measles, mumps, rhinovirus, and respiratory syncytial virus …

The ability of a pathogen to evade host immunity successfully, in contrast to the host's
capacity to defend itself against a foreign invader, is a complex struggle, in which …

The human innate host defense molecules, SP-A1 and SP-A2 variants, differentially affect
survival after infection in mice and in lung transplant patients. SP-A interacts with the …

Pulmonary surfactant and its components are essential for normal lung function and are
involved in local host defense. Surfactant protein (SP)—A and SP-D bind to and modulate …

Ozone exposure can cause inflammation and impaired lung function. Human surfactant
protein A (SP-A) may play a role in inflammation by modulating cytokine production by …

Although the lung is protected by classic innate and adaptive immune mechanisms, another
unique local immunoregulatory system involving pulmonary surfactant is described in this …

Surfactant protein A (SP-A) enhances phagocytosis of Pseudomonas aeruginosa. SP-A1
and SP-A2 encode human (h) SP-A; SP-A2 products enhance phagocytosis more than SP …

Ambient ozone is a criteria air pollutant that impacts both human morbidity and mortality. The
effect of ozone inhalation includes both toxicity to lung tissue and alteration of the host …

Lysozyme and 10 other proteins are solubilized in reverse micelles formed by 0.1 M sodium
di-2-ethyl-hexylsulfosuccinate and 2.0-2.5 M water (pH 7.4) in isooctane solvent. Exposure …

The human surfactant protein A (SP-A) locus consists of two functional genes, SP-A1 and SP-
A2, with several alleles characterized for each gene. Functional variations between SP-A1 …