The pathophysiology of sepsis and its accompanying systemic inflammatory response
syndrome (SIRS) and the events that lead to multiorgan failure and death are poorly …

Sepsis remains a major cause of morbidity and mortality mainly because of sepsis-induced
multiple organ dysfunction. In contrast to preclinical studies, most clinical trials of promising …

Background: Although estimation of energy needs by mathematical equation is common in
practice, there is relatively little validation data for the equations. This is especially true at the …

Gram-negative bacteria remain the leading cause of sepsis, a disease that is consistently in
the top 10 causes of death internationally. Curing bacteremia alone does not necessarily …

Introduction Gram-negative bacteria release outer membrane vesicles (OMVs) during
growth that contain various membrane components involved in eliciting an inflammatory …

Background: Indirect calorimetry is the criterion method for assessment of energy
expenditure in critically ill patients but is decidedly uncommon. Thus, calculation methods …

RESUMEN A pesar de los avances de las técnicas quirúrgicas, anestésicas,
microbiológicas, así como de la ingeniería genética y la biotecnología, las infecciones …

The aim of this study was to investigate the protective effect of erythropoietin (EPO) against
acute myocardial injury and its underlying mechanisms. Mice (n= 146) were randomly …

Sepsis is a systemic inflammatory response syndrome with a suspected or proven infection
caused by any pathogen or a clinical syndrome associated with a high probability of …

BACKGROUND: High mobility group box 1 protein (HMGB1) is a highly conserved,
ubiquitous protein in the nuclei and cytoplasm of nearly all cell types. HMGB1 is secreted …