Pharmacological properties of chalcones: a review of preclinical including molecular mechanisms and clinical evidence
Chalcones are among the leading bioactive flavonoids with a therapeutic potential
implicated to an array of bioactivities investigated by a series of preclinical and clinical …
implicated to an array of bioactivities investigated by a series of preclinical and clinical …
Activation of Nrf2 signaling pathway by natural and synthetic chalcones: A therapeutic road map for oxidative stress
Introduction: Nuclear factor erythroid 2-related factor 2 (Nrf2) signaling pathway plays a key
role in diverse gene expressions responsible for protection against oxidative stress and …
role in diverse gene expressions responsible for protection against oxidative stress and …
New chalcone derivatives as potential antimicrobial and antioxidant agent
Seven chalcone derivatives were synthesized by the Claisen-Schmidt condensation. The
structures of the compounds were confirmed by spectral data (Ultraviolet/visible, infrared …
structures of the compounds were confirmed by spectral data (Ultraviolet/visible, infrared …
An overview of NRF2-activating compounds bearing α, β-unsaturated moiety and their antioxidant effects
MC Egbujor, B Buttari, E Profumo… - International Journal of …, 2022 - mdpi.com
The surge of scientific interest in the discovery of Nuclear Factor Erythroid 2 (NFE2)-Related
Factor 2 (NRF2)-activating molecules underscores the importance of NRF2 as a therapeutic …
Factor 2 (NRF2)-activating molecules underscores the importance of NRF2 as a therapeutic …
[HTML][HTML] Development of a blue innovative antioxidant, biodegradable packaging material with Clitoria ternatea L. flos
M Szymański, M Pawlik, R Dobrucka - Food Bioscience, 2024 - Elsevier
Today, the packaging industry, and in particular the plastic packaging industry, are going to
experience a number of challenges as a result of the provisions included in the directive on …
experience a number of challenges as a result of the provisions included in the directive on …
Design, synthesis, characterization and in vivo antidiabetic activity evaluation of some chalcone derivatives
S Welday Kahssay, GS Hailu… - Drug Design …, 2021 - Taylor & Francis
Background Diabetes is one of the growing health problems worldwide, and scientists have
been striving to find effective treatment methods. In this regard, chalcones have frequently …
been striving to find effective treatment methods. In this regard, chalcones have frequently …
Synthesis and biological activity of new chalcone scaffolds as prospective antimicrobial agents
Chalcones are open-chain flavonoids which contains two aromatic rings are joined by 3-
carbons α-, β-unsaturated carbonyl chain. The, β-unsaturated ketonic group which is liable …
carbons α-, β-unsaturated carbonyl chain. The, β-unsaturated ketonic group which is liable …
Synthesis, biological evaluation and molecular docking study of oxindole based chalcone analogues as potent anti-Alzheimer agents
With the goal of developing potential cholinesterase pharmaco-therapeutics, a new class of
thirty analogs oxindole-based chalcone were synthesized by reacting nitro substituted …
thirty analogs oxindole-based chalcone were synthesized by reacting nitro substituted …
Chalcones and flavanones bearing hydroxyl and/or methoxyl groups: Synthesis and biological assessments
GP Rosa, AML Seca, MC Barreto, AMS Silva… - Applied Sciences, 2019 - mdpi.com
Chalcones and flavanones are isomeric structures and also classes of natural products,
belonging to the flavonoid family. Moreover, their wide range of biological activities makes …
belonging to the flavonoid family. Moreover, their wide range of biological activities makes …
Microwave assisted green synthesis of benzimidazole derivatives and evaluation of their anticonvulsant activity
Background: Benzimidazole is the fused heterocyclic aromatic compound. It is an essential
pharmacophore and privileged structure for the development of new drug molecules. These …
pharmacophore and privileged structure for the development of new drug molecules. These …