Objective To discuss the current available techniques for intraoperative margin assessment
in the surgical treatment of oral squamous cell carcinoma (OSCC) through a review of the …

Optical endoscopy is the primary diagnostic and therapeutic tool for management of
gastrointestinal (GI) malignancies. Most GI neoplasms arise from precancerous lesions; …

Microscopic evaluation of resected tissue plays a central role in the surgical management of
cancer. Because optical microscopes have a limited depth-of-field (DOF), resected tissue is …

The advent of fluorescence imaging (FI) for cancer cell detection in the field of oncology is
promising for both cancer screening and surgical resection. Particularly, FI in cancer …

Background and study aims: Distinguishing sessile serrated adenomas/polyps (SSA/Ps)
from non-neoplastic tissue may be challenging when white-light endoscopy (WLE) is used …

Fiber optic microendoscopy has shown promise for visualization of molecular contrast
agents used to study disease in vivo. However, fiber optic microendoscopes have limited …

OBJECTIVES: High-resolution microendoscopy (HRME) is a low-cost,“optical biopsy”
technology that allows for subcellular imaging. The purpose of this study was to determine …

Fiber-optic microendoscopes have shown promise to image the changes in nuclear
morphometry that accompany the development of precancerous lesions in tissue with …

Fiber-optic endomicroscopy is a minimally invasive method to image cellular morphology in
vivo. Using a coherent fiber bundle as an image relay, it allows additional imaging optics to …

Intraepithelial dysplasia of the oral mucosa typically originates in the proliferative cell layer
at the basement membrane and extends to the upper epithelial layers as the disease …