Tolerance and innate immunity shape the development of postpartum uterine disease and the impact of endometritis in dairy cattle

IM Sheldon, JG Cronin… - Annual review of animal …, 2019 - annualreviews.org
Bacteria are ubiquitous in the bovine uterus after parturition, but 50 years ago, cows
tolerated these bacteria and few animals developed uterine disease. Now, up to 40% of …

Modulation of immune function in the bovine uterus peripartum

OB Pascottini, SJ LeBlanc - Theriogenology, 2020 - Elsevier
There is a high risk of clinical or subclinical reproductive tract disease in the postpartum
period in dairy cows. An integrated process of adaptive events should occur synchronously …

General and comparative aspects of endometritis in domestic species: A review

OB Pascottini, C Aurich, G England… - … in Domestic Animals, 2023 - Wiley Online Library
Endometritis is a leading cause of sub‐and infertility in domestic animal species. The
healthy uterus is colonized by commensal bacteria, viruses and yeast/fungi that represent …

[HTML][HTML] Symposium review: Mechanisms of disruption of fertility by infectious diseases of the reproductive tract

RO Gilbert - Journal of dairy science, 2019 - Elsevier
Diseases of postpartum dairy cows impair reproductive processes, resulting in prolonged
anestrus, reduced conception, and increased pregnancy attrition, regardless of whether the …

Maladaptation to the transition period and consequences on fertility of dairy cows

OB Pascottini, JLMR Leroy… - Reproduction in domestic …, 2022 - Wiley Online Library
After parturition, dairy cows undergo a plethora of metabolic, inflammatory, and immunologic
changes to adapt to the onset of lactation. These changes are mainly due to the homeorhetic …

Effect of anti-inflammatory treatment on systemic inflammation, immune function, and endometrial health in postpartum dairy cows

OB Pascottini, SJ Van Schyndel, JFW Spricigo… - Scientific reports, 2020 - nature.com
Systemic inflammation (SI) is increasingly studied in several species because it may be
central in many metabolic disturbances and be a risk factor for clinical disease. This proof-of …

[HTML][HTML] Postpartum reproductive disease and fertility in dairy cows

SJ LeBlanc - animal, 2023 - Elsevier
This paper reviews recent data and concepts on metritis, purulent vaginal discharge (PVD),
and endometritis in dairy cows and the ways in which these diseases affect reproductive …

The negative impact of lameness on dairy cow reproduction

G Tsousis, C Boscos… - Reproduction in Domestic …, 2022 - Wiley Online Library
Lameness in modern dairy farms is a prevalent disorder that negatively affects all aspects of
production. Additionally, is a prevailing contributor to the decreased welfare of cows. Recent …

Inflammation: friend or foe of bovine reproduction?

S Chastant, M Saint-Dizier - Animal reproduction, 2019 - SciELO Brasil
Inflammation is not only the first line of defense of the organism but is also required in many
reproductive processes such as ovulation, corpus luteum development, luteolysis, uterine …

[HTML][HTML] Associations of postpartum health with progesterone after insemination and endocrine signaling during early pregnancy in dairy cows

TC Bruinjé, EI Morrison, ES Ribeiro, DL Renaud… - Journal of Dairy …, 2024 - Elsevier
Our objective was to investigate associations of postpartum health with serum progesterone
(P4) concentrations after first artificial insemination (AI), expression of interferon-stimulated …