Macrophages play an important role in a wide variety of physiologic and pathologic
processes. Plasticity and functional polarization are hallmarks of macrophages …

Inflammation, especially chronic inflammation, plays a pivotal role in tumorigenesis and
metastasis through various mechanisms and is now recognized as a hallmark of cancer and …

Colorectal cancer (CRC) is a predominant life‐threatening cancer, with liver and peritoneal
metastases as the primary causes of death. Intestinal inflammation, a known CRC risk factor …

Atrazine (ATR) is a commonly used triazine herbicide, which will remain in the water source,
soil and biological muscle tissue for a long time, threatening the survival of related …

Mesenchymal stromal cells (MSCs) currently constitute the most frequently used cell type in
advanced therapies with different purposes, most of which are related with inflammatory …

Treatments that block tumour necrosis factor (TNF) have major beneficial effects in several
autoimmune and rheumatic diseases, including rheumatoid arthritis. However, some …

Effective tumor regression has been observed with chimeric antigen receptor (CAR) T cells;
however, the development of an affordable, safe, and effective CAR-T cell treatment remains …

The intestine and skin are distinct microenvironments with unique physiological functions
and are continually exposed to diverse environmental challenges. Host adaptation at these …

Dendritic cells (DCs) play a pivotal role in initiating antigen-specific tumor immunity.
However, the abnormal function of DCs owing to the immunosuppressive tumor …

Smoking is a serious global health issue. Cigarette smoking contains over 7000 different
chemicals. The main harmful components include nicotine, acrolein, aromatic hydrocarbons …