The cadherin-catenin adhesion complex is the key component of the intercellular adherens
junction (AJ) that contributes both to tissue stability and dynamic cell movements in epithelial …

Epithelial barrier function is regulated by a family of transmembrane proteins known as
claudins. Functional tight junctions are formed when claudins interact with other …

Colloidal particles with mobile binding molecules constitute a powerful platform for probing
the physics of self-assembly. Binding molecules are free to diffuse and rearrange on the …

Cadherin transmembrane proteins are responsible for intercellular adhesion in all biological
tissues and modulate tissue morphogenesis, cell motility, force transduction, and …

Just like atoms combine into molecules, colloids can self-organize into predetermined
structures according to a set of design principles. Controlling valence—the number of …

Tissue-wide patterning is essential to multicellular development, requiring cells to
individually generate polarity axes and coordinate them in space and time with neighbors …

Particles with ligand–receptor contacts bind and unbind fluctuating “legs” to surfaces, whose
fluctuations cause the particle to diffuse. Quantifying the diffusion of such “nanoscale …

E-cadherin plays a central role in cell-cell adhesion. The ectodomains of wild-type cadherins
form a crystalline-like two-dimensional lattice in cell-cell interfaces mediated by both trans …

Cell adhesions to the extracellular matrix and to neighboring cells are fundamental to cell
behavior and have also been implemented into minimal synthetic cells, which are …

Inspired by how cells pack in dense biological tissues, we design 2D and 3D amorphous
materials that possess a complete photonic bandgap. A physical parameter based on how …