Cucurbituril‐based supramolecular polymers for biomedical applications

Z Wang, C Sun, K Yang, X Chen… - Angewandte Chemie …, 2022 - Wiley Online Library
Supramolecular polymers (SPs) have attracted broad interest because of their intriguing
features and functions. Host–guest interactions often impart tunable physicochemical …

[HTML][HTML] Supramolecular engineering of hydrogels for drug delivery

S Bernhard, MW Tibbitt - Advanced Drug Delivery Reviews, 2021 - Elsevier
Supramolecular binding motifs are increasingly employed in the design of biomaterials. The
ability to rationally engineer specific yet reversible associations into polymer networks with …

Overcoming the blood–brain barrier: the role of nanomaterials in treating neurological diseases

D Furtado, M Björnmalm, S Ayton, AI Bush… - Advanced …, 2018 - Wiley Online Library
Therapies directed toward the central nervous system remain difficult to translate into
improved clinical outcomes. This is largely due to the blood–brain barrier (BBB), arguably …

Multifunctional Mesoporous Polydopamine‐Based Systematic Delivery of STING Agonist for Enhanced Synergistic Photothermal‐Immunotherapy

W Zeng, Z Li, Q Huang, C Ding, L Yang… - Advanced Functional …, 2024 - Wiley Online Library
The therapeutic application of STING agonists in various malignancies has been limited by
factors such as the inability of systemic administration and the immunosuppressive tumor …

Challenges and opportunities of functionalized cucurbiturils for biomedical applications

H Yin, Q Cheng, D Bardelang, R Wang - JACS Au, 2023 - ACS Publications
Cucurbit [n] uril (CB [n]) macrocycles (especially CB [5] to CB [8]) have shown exceptional
attributes since their discovery in 2000. Their stability, water solubility, responsiveness to …

Drug delivery by supramolecular design

MJ Webber, R Langer - Chemical Society Reviews, 2017 - pubs.rsc.org
The rational design of drug delivery approaches leveraging supramolecular chemistry
(ie,“chemistry beyond the molecule”) has garnered significant interest in recent years toward …

Ring opening polymerization of α-amino acids: advances in synthesis, architecture and applications of polypeptides and their hybrids

AR Mazo, S Allison-Logan, F Karimi… - Chemical society …, 2020 - pubs.rsc.org
Polypeptides have attracted considerable attention in recent decades due to their inherent
biodegradability and tunable cytocompatibility. Macromolecular design in conjunction with …

[HTML][HTML] Polymer bioconjugates: Modern design concepts toward precision hybrid materials

C Chen, DYW Ng, T Weil - Progress in Polymer Science, 2020 - Elsevier
The conjugation of synthetic polymers with various biomolecules provides an easy access to
biohybrid materials which combine advantages from both the synthetic world and Nature …

Cucurbituril‐based biomacromolecular assemblies

YH Liu, YM Zhang, HJ Yu, Y Liu - Angewandte Chemie, 2021 - Wiley Online Library
The construction of controlled biomacromolecular assemblies has become a thriving area of
supramolecular chemistry. In this context, cucurbiturils (CBs), a class of macrocyclic …

[HTML][HTML] Cell membrane-derived vesicles for delivery of therapeutic agents

QV Le, J Lee, H Lee, G Shim, YK Oh - Acta Pharmaceutica Sinica B, 2021 - Elsevier
Cell membranes have recently emerged as a new source of materials for molecular delivery
systems. Cell membranes have been extruded or sonicated to make nanoscale vesicles …