Sarcopenia during COVID-19 lockdown restrictions: long-term health effects of short-term muscle loss

R Kirwan, D McCullough, T Butler, F Perez de Heredia… - GeroScience, 2020 - Springer
The COVID-19 pandemic is an extraordinary global emergency that has led to the
implementation of unprecedented measures in order to stem the spread of the infection …

AMP-activated protein kinase: the current landscape for drug development

GR Steinberg, D Carling - Nature reviews Drug discovery, 2019 - nature.com
Since the discovery of AMP-activated protein kinase (AMPK) as a central regulator of energy
homeostasis, many exciting insights into its structure, regulation and physiological roles …

[HTML][HTML] Obesity in adults: a clinical practice guideline

S Wharton, DCW Lau, M Vallis, AM Sharma, L Biertho… - Cmaj, 2020 - Can Med Assoc
This guideline update reflects substantial advances in the epidemiology, determinants,
pathophysiology, assessment, prevention and treatment of obesity, and shifts the focus of …

Cancer-associated cachexia

VE Baracos, L Martin, M Korc, DC Guttridge… - Nature reviews Disease …, 2018 - nature.com
Cancer-associated cachexia is a disorder characterized by loss of body weight with specific
losses of skeletal muscle and adipose tissue. Cachexia is driven by a variable combination …

Obesity and pregnancy: mechanisms of short term and long term adverse consequences for mother and child

PM Catalano, K Shankar - Bmj, 2017 - bmj.com
Obesity is the most common medical condition in women of reproductive age. Obesity during
pregnancy has short term and long term adverse consequences for both mother and child …

Impact of weight bias and stigma on quality of care and outcomes for patients with obesity

SM Phelan, DJ Burgess, MW Yeazel… - Obesity …, 2015 - Wiley Online Library
The objective of this study was to critically review the empirical evidence from all relevant
disciplines regarding obesity stigma in order to (i) determine the implications of obesity …

Joint international consensus statement for ending stigma of obesity

F Rubino, RM Puhl, DE Cummings, RH Eckel… - Nature medicine, 2020 - nature.com
People with obesity commonly face a pervasive, resilient form of social stigma. They are
often subject to discrimination in the workplace as well as in educational and healthcare …

Food timing, circadian rhythm and chrononutrition: a systematic review of time-restricted eating's effects on human health

R Adafer, W Messaadi, M Meddahi, A Patey… - Nutrients, 2020 - mdpi.com
Introduction: Recent observations have shown that lengthening the daily eating period may
contribute to the onset of chronic diseases. Time-restricted eating (TRE) is a diet that …

Obesity energetics: body weight regulation and the effects of diet composition

KD Hall, J Guo - Gastroenterology, 2017 - Elsevier
Weight changes are accompanied by imbalances between calorie intake and expenditure.
This fact is often misinterpreted to suggest that obesity is caused by gluttony and sloth and …

β3-Adrenergic receptor downregulation leads to adipocyte catecholamine resistance in obesity

JM Valentine, M Ahmadian, O Keinan… - The Journal of …, 2022 - Am Soc Clin Investig
The dysregulation of energy homeostasis in obesity involves multihormone resistance.
Although leptin and insulin resistance have been well characterized, catecholamine …