[HTML][HTML] Radiopharmaceutical therapy in cancer: clinical advances and challenges
Radiopharmaceutical therapy (RPT) is emerging as a safe and effective targeted approach
to treating many types of cancer. In RPT, radiation is systemically or locally delivered using …
to treating many types of cancer. In RPT, radiation is systemically or locally delivered using …
Fluorescent chemical probes for accurate tumor diagnosis and targeting therapy
Surgical resection of solid tumors is currently the gold standard and preferred therapeutic
strategy for cancer. Chemotherapy drugs also make a significant contribution by inhibiting …
strategy for cancer. Chemotherapy drugs also make a significant contribution by inhibiting …
Low-dose targeted radionuclide therapy renders immunologically cold tumors responsive to immune checkpoint blockade
RB Patel, R Hernandez, P Carlson… - Science translational …, 2021 - science.org
Molecular and cellular effects of radiotherapy on tumor microenvironment (TME) can help
prime and propagate antitumor immunity. We hypothesized that delivering radiation to all …
prime and propagate antitumor immunity. We hypothesized that delivering radiation to all …
Beyond the margins: real-time detection of cancer using targeted fluorophores
RR Zhang, AB Schroeder, JJ Grudzinski… - Nature reviews Clinical …, 2017 - nature.com
Over the past two decades, synergistic innovations in imaging technology have resulted in a
revolution in which a range of biomedical applications are now benefiting from fluorescence …
revolution in which a range of biomedical applications are now benefiting from fluorescence …
[HTML][HTML] The promise of combining radiation therapy with immunotherapy
The development of immunotherapy in oncology builds upon many years of scientific
investigation into the cellular mechanics underlying interactions between tumor cells and …
investigation into the cellular mechanics underlying interactions between tumor cells and …
[HTML][HTML] A bright future for precision medicine: advances in fluorescent chemical probe design and their clinical application
The Precision Medicine Initiative aims to use advances in basic and clinical research to
develop therapeutics that selectively target and kill cancer cells. Under the same doctrine of …
develop therapeutics that selectively target and kill cancer cells. Under the same doctrine of …
[HTML][HTML] Fluorescence-guided surgery: a review on timing and use in brain tumor surgery
Fluorescence-guided surgery (FGS) allows surgeons to have improved visualization of
tumor tissue in the operating room, enabling maximal safe resection of malignant brain …
tumor tissue in the operating room, enabling maximal safe resection of malignant brain …
Radiotheranostics in cancer diagnosis and management
The fundamental foundation for precision medicine is accurate and specific targeting of
cancer cells. Advances in the understanding of cancer biology, developments in diagnostic …
cancer cells. Advances in the understanding of cancer biology, developments in diagnostic …
[HTML][HTML] Temporal analysis of type 1 interferon activation in tumor cells following external beam radiotherapy or targeted radionuclide therapy
Rationale: Clinical interest in combining targeted radionuclide therapies (TRT) with
immunotherapies is growing. External beam radiation therapy (EBRT) activates a type 1 …
immunotherapies is growing. External beam radiation therapy (EBRT) activates a type 1 …
[HTML][HTML] Clinical advances and perspectives in targeted radionuclide therapy
N Lepareur, B Ramée, M Mougin-Degraef… - Pharmaceutics, 2023 - mdpi.com
Targeted radionuclide therapy has become increasingly prominent as a nuclear medicine
subspecialty. For many decades, treatment with radionuclides has been mainly restricted to …
subspecialty. For many decades, treatment with radionuclides has been mainly restricted to …