CCDC (coiled-coil domain-containing) is a coiled helix domain that exists in natural proteins.
There are about 180 CCDC family genes, encoding proteins that are involved in intercellular …

Simple Summary Retrospective studies of common malignancies such as head and neck
cancer often report lower incidence and/or better outcomes for patients incidentally treated …

Abstract miR-17-5p has been found to be involved in the proliferation and metastasis of
colorectal cancer (CRC), and N 6-methyladenosine (m6A) modification is the most common …

Abstract Background Enolase 2 (ENO2) is a crucial glycolytic enzyme in cancer metabolic
process and acts as a “moonlighting” protein to play various functions in diverse cellular …

Pattern-recognition receptors (PRRs) are critical to recognizing endogenous and exogenous
threats to mount a protective proinflammatory innate immune response. PRRs may be …

Glycolytic metabolism may account for antitumor immunity failure. Pyruvate kinase M2
(PKM2) and platelet phosphofructokinase (PFKP), two key enzymes involved in the …

Calcium nanoparticles have been investigated for applications, such as drug and gene
delivery. Additionally, Ca2+ serves as a crucial second messenger in the activation of …

Abstract Background Bladder cancer (BCa) is a highly malignant tumor, and if left untreated,
it can develop severe hematuria and tumor metastasis, thereby endangering the patient's …

Malignant proliferation and abundant angiogenesis are major causes of lung
adenocarcinoma (LUAD) with high morbidity and mortality. Therefore, the exploration of the …

Chemotherapeutic agents can inhibit the proliferation of malignant cells due to their
cytotoxicity, which is limited by collateral damage. Dihydroartemisinin (DHA), has a selective …