Cell-based therapies have generated great interest in the scientific and medical
communities, and stem cells in particular are very appealing for regenerative medicine, drug …

Cellular microarrays are powerful experimental tools for high-throughput screening of large
numbers of test samples. Miniaturization increases assay throughput while reducing reagent …

Traditional antibody-based affinity sensing strategies employ multiple reagents and washing
steps and are unsuitable for real-time detection of analyte binding. Aptamers, on the other …

We present here a new method to enhance the detection of secreted cytokines and
chemokines from single human mononuclear cells. The technique uses a hybridization …

Characterization of leukocytes is an integral part of blood analysis and blood-based
diagnostics. In the present paper, we combine lensless holographic imaging with antibody …

This paper demonstrates a novel strategy for site-selective cell adhesion and in situ
cultivation of living cells, integrated with real-time monitoring of cellular small biomolecules …

During the development of an organism, cells are exposed to a myriad of signals, structural
components and scaffolds, which collectively make up the cellular microenvironment. The …

Cytokines play important roles in the immune system and have been regarded as
biomarkers. While single cytokine is not specific and accurate enough to meet the strict …

Heterogeneity of cell populations in various biological systems has been widely recognized,
and the highly heterogeneous nature of cancer cells has been emerging with clinical …

We demonstrate the patterned biofunctionalization of antifouling hyperbranched
polyglycerol (HPG) coatings on silicon and glass substrates. The ultralow fouling HPG …