The broad-spectrum antiparasitic drug ivermectin was licensed for use against
onchocerciasis in 1987, yet the mechanisms by which it exerts a fast decrease and long …

Mathematical modelling of helminth infections has the potential to inform policy and guide
research for the control and elimination of human helminthiases. However, this potential …

Zoonotic spillover and hybridization of parasites are major emerging public and veterinary
health concerns at the interface of infectious disease biology, evolution, and control …

Population ecology, the discipline that studies the dynamics of species' populations and how
they interact with the environment, has been one of the most prolific fields of ecology and …

Malaria parasites develop as oocysts in the mosquito for several days before they are able
to infect a human host. During this time, mosquitoes take bloodmeals to replenish their …

Individuals vary broadly in their response to vaccination and subsequent challenge
infection, with poor vaccine responders causing persistence of both infection and …

Background Morbidity due to Schistosoma haematobium and hookworm infections is
marked in those with intense co-infections by these parasites. The development of a spatial …

Human onchocerciasis (river blindness) is one of the few neglected tropical diseases
(NTDs) whose control strategies have been informed by mathematical modelling. With the …

Background To date schistosomiasis control programmes based on chemotherapy have
largely aimed at controlling morbidity in treated individuals rather than at suppressing …

Background Density dependence in helminth establishment and heterogeneity in exposure
to infection are known to drive resilience to interventions based on mass drug administration …