Radiotherapy toxicity

D De Ruysscher, G Niedermann, NG Burnet… - Nature Reviews …, 2019 - nature.com
Radiotherapy is used in> 50% of patients with cancer, both for curative and palliative
purposes. Radiotherapy uses ionizing radiation to target and kill tumour tissue, but normal …

Common oral complications of head and neck cancer radiation therapy: mucositis, infections, saliva change, fibrosis, sensory dysfunctions, dental caries, periodontal …

HY Sroussi, JB Epstein, RJ Bensadoun… - Cancer …, 2017 - Wiley Online Library
Patients undergoing radiation therapy for the head and neck are susceptible to a significant
and often abrupt deterioration in their oral health. The oral morbidities of radiation therapy …

New frontiers in the pathobiology and treatment of cancer regimen-related mucosal injury

M Cinausero, G Aprile, P Ermacora, D Basile… - Frontiers in …, 2017 - frontiersin.org
Mucositis is a common complication of chemotherapy, radiotherapy and targeted agents. It
often affects compliance to anticancer therapies as it frequently causes schedule delays …

Systematic review of anti-inflammatory agents for the management of oral mucositis in cancer patients and clinical practice guidelines

A Ariyawardana, KKF Cheng, A Kandwal, V Tilly… - Supportive Care in …, 2019 - Springer
Purpose The aim of this systematic review was to update the clinical practice guidelines for
the use of anti-inflammatory agents in the prevention and/or treatment of oral mucositis …

Status of treatment and prophylaxis for radiation-induced oral mucositis in patients with head and neck cancer

S Liu, Q Zhao, Z Zheng, Z Liu, L Meng, L Dong… - Frontiers in …, 2021 - frontiersin.org
Radiation-induced oral mucositis (RIOM) is one of the most frequent complications in head
and neck cancer (HNC) patients undergoing radiotherapy (RT). It is a type of mucosal injury …

Interventions for the Prevention of oral mucositis in patients receiving Cancer Treatment: evidence from Randomised controlled trials

G Colella, CE Boschetti, R Vitagliano, C Colella… - Current …, 2023 - mdpi.com
Oral mucositis is a common and most debilitating complication associated with cancer
therapy. Despite the significant clinical and economic impact of this condition, there is little to …

Management of chemo/radiation-induced oral mucositis in patients with head and neck cancer: A review of the current literature

D Moslemi, AM Nokhandani, MT Otaghsaraei… - Radiotherapy and …, 2016 - Elsevier
Oropharyngeal mucositis is an important complication in non-surgical cancer treatments. It
represents the major complication in radiotherapy of tumors located in head and neck areas …

Ionizing radiation-induced cellular senescence promotes tissue fibrosis after radiotherapy. A review

HQ Nguyen, NH To, P Zadigue, S Kerbrat… - Critical reviews in …, 2018 - Elsevier
Ionizing radiation-exposure induces a variety of cellular reactions, such as senescence and
apoptosis. Senescence is a permanent arrest state of the cell division, which can be …

A systematic review of interventions to mitigate radiotherapy-induced oral mucositis in head and neck cancer patients

C Davy, S Heathcote - Supportive Care in Cancer, 2021 - Springer
Background Oral mucositis is a debilitating consequence of radiotherapy in patients with
head and neck cancers. Radiation-induced oral mucositis (RIOM) can cause pain and …

Protection against radiotherapy-induced toxicity

S Hall, S Rudrawar, M Zunk, N Bernaitis, D Arora… - Antioxidants, 2016 - mdpi.com
Radiation therapy is a highly utilized therapy in the treatment of malignancies with up to 60%
of cancer patients receiving radiation therapy as a part of their treatment regimen. Radiation …