Genetic variation, which is generated by mutation, recombination and gene flow, can reduce
the mean fitness of a population, both now and in the future. This 'genetic load'has been …

Deleterious mutations decrease reproductive fitness and are ubiquitous in genomes. Given
that many organisms face ongoing threats of extinction, there is interest in elucidating the …

Domestication of horses fundamentally transformed long-range mobility and warfare.
However, modern domesticated breeds do not descend from the earliest domestic horse …

The current rate of species extinction is rapidly approaching unprecedented highs, and life
on Earth presently faces a sixth mass extinction event driven by anthropogenic activity …

Despite the substantial role that chickens have played in human societies across the world,
both the geographic and temporal origins of their domestication remain controversial. To …

The domestication of animals led to a major shift in human subsistence patterns, from a
hunter–gatherer to a sedentary agricultural lifestyle, which ultimately resulted in the …

Natural history collections are invaluable repositories of biological information that provide
an unrivaled record of Earth's biodiversity. Museum genomics—genomics research using …

This review presents a broader approach to the implementation and study of runs of
homozygosity (ROH) in animal populations, focusing on identifying and characterizing ROH …

Horse domestication revolutionized warfare and accelerated travel, trade, and the
geographic expansion of languages. Here, we present the largest DNA time series for a non …

The Eneolithic Botai culture of the Central Asian steppes provides the earliest
archaeological evidence for horse husbandry,~ 5500 years ago, but the exact nature of early …