Microwave induced green synthesis: sustainable Technology for efficient development of bioactive pyrimidine scaffolds

BM Sahoo, BK Banik, BVVR Kumar… - Current Medicinal …, 2023 - ingentaconnect.com
Microwave radiation is used as a heating source during the synthesis of heterocyclic
compounds. The heating mechanisms involved in microwave-induced synthesis include …

Medicinal perspective of a promising scaffold–dihydropyrimidinones: A review

BH Sarvaiya, PI Vaja, NA Paghdar… - Journal of Heterocyclic …, 2024 - Wiley Online Library
Dihydropyrimidinones (DHMPs) are the most important pharmacophore in Medicinal
Chemistry. The synthetic approach for deriving DHMPs involves the Biginelli reaction or a …

Design and Rapid Microwave Irradiated One-Pot Synthesis of Tetrahydropyrimidine Derivatives and Their Screening In Vitro Antidiabetic Activity

JN Lalpara, SD Hadiyal, AJ Radia… - Polycyclic Aromatic …, 2022 - Taylor & Francis
A rapid and efficient method has been developed for one-pot synthesis of some newly
designed tetrahydropyrimidine derivatives with aid of 1, 3, 4-oxadiazole containing …

[PDF][PDF] Synthesis, Characterization, and DFT Calculation of Some New Pyrimidine Derivatives and Theoretical Studies on the Corrosion Inhibition Performance

E Akbas, A Ruzgar, A Cagla, S Ertan - Iranian Journal of Chemistry and …, 2022 - ijcce.ac.ir
In this study, 5-benzoyl-6-phenyl-4-(4-(trifluoromethoxy) phenyl)-1, 2, 3, 4-
tetrahydroxypyrimidine (1); 5-benzoyl-6-phenyl-4-(4-(trifluoromethoxy) phenyl)-1, 2, 3, 4 …

Synthesis, theoretical calculation, electrochemistry and total antioxidant capacity of 5-benzoyl-6-phenyl-4-(4-methoxyphenyl)-1, 2, 3, 4-tetrahydro-2-thioxopyrimidine …

E Ergan, E Akbas, A Levent, E Sahin, M Konus… - Journal of Molecular …, 2017 - Elsevier
Benzoyl-6-phenyl-4-(4-mehtoxyphenyl)-1, 2, 3, 4-tetrahydro-2-thioxopyrimidine (1) have
been prepared via Biginelli cyclocondensation reaction in acetic acid under reflux condition …

Synthesis and evaluation of novel N-(4′-arylpyrimidin-2′-yl) sulfonylurea derivatives as potential antifungal agents

W Chen, Y Li, Y Shi, W Wei, Y Chen, Y Li, J Liu… - Chemical Research in …, 2015 - Springer
Sulfonylureas (SUs) are potent and selective inhibitors of acetohydroxyacid synthase and
has been used as herbicides. Some SUs also displayed other biological activities. In order …

Metal-Free Synthesis of Pyrimidinone Derivatives via Biginelli Reaction Using Aqueous NaICl2

NT Hatvate, SM Ghodse, KN Mundlod… - Letters in Organic …, 2020 - ingentaconnect.com
Metal-free synthesis of pyrimidinone (alky/aryl) via Biginelli reaction in the presence of
aqueous sodium dichloroiodate (NaICl2) was studied under reflux conditions. Herein, we …

Synthesis and Antibacterial Activity of Novel (4‐Fluorophenyl)(4‐(naphthalen‐2‐yl)‐6‐aryl‐2‐thioxo‐2,3‐dihydropyrimidin‐1(6H)‐yl)methanone Derivatives

T Sekhar, P Thriveni, M Hari Krishna… - Journal of …, 2019 - Wiley Online Library
A novel series of (4‐fluorophenyl)(4‐(naphthalen‐2‐yl)‐6‐aryl‐2‐thioxo‐2, 3‐
dihydropyrimidin‐1 (6H)‐yl) methanone derivatives were synthesized from reaction of 6 …

Microwave-Assisted Synthesis of New Dihydropyrimidine Derivatives and Mechanism of the Reactions

E Akbas, E Sahin, E Yildiz, B Anil… - Letters in Organic …, 2013 - ingentaconnect.com
5-benzoyl-4-aryl-6-phenyl-1, 2, 3, 4-tetrahydro-2-thioxopyrimidines were synthesized via
Biginelli cyclocondensation reaction. The diethyl 2-(4-aryl-5-benzoyl-6-phenyl-3, 4 …