Nitric oxide (NO) is formed during the oxidation of L-arginine to L-citrulline by the action of
multiple isoenzymes of NO synthase (NOS): neuronal NOS (nNOS), endotelial NOS (eNOS) …

Cyclophosphamide (CTX) is a chemotherapeutic agent widely used to treat ovarian, breast,
and hematological cancers as well as autoimmune disorders. Such chemotherapy is …

Background: Identification of female reproductive toxicants is currently based largely on
integrated epidemiological and in vivo toxicology data and, to a lesser degree, on …

Abstract Fluorene-9-bisphenol (BHPF), a substitute for bisphenol A, is a chemical
component of plastics for industrial production. There is evidence that BHPF exerts an …

Glyphosate is the most popular herbicide used in modern agriculture, and its use has been
increasing substantially since its introduction. Accordingly, glyphosate exposure from food …

Background The average age of childbearing has increased over the years contributing to
infertility, miscarriages, and chromosomal abnormalities largely invoked by an age-related …

Endometriosis is a chronic inflammatory gynecologic disorder characterized by the presence
of endometrial glands and stroma throughout the abdominopelvic cavity, including the …

Reproductive dysfunction associated with obesity is increasing among women of
reproductive age, including infertility and increasing risk of miscarriage. In females …

Premature ovarian insufficiency (POI) is a frequent long-term complication of classic
galactosemia. The majority of women with this disorder develop POI, however rare …

Recent studies have revealed that acrolein, a commonly found toxin and a potent metabolite
of cyclophosphamide (CTX), can cause deterioration of mouse oocyte quality through a …