MicroRNAs and apoptosis in colorectal cancer

H Wang - International journal of molecular sciences, 2020 - mdpi.com
Colorectal cancer (CRC) is the third leading cause of cancer death in the world, and its
incidence is rising in developing countries. Treatment with 5-Fluorouracil (5-FU) is known to …

Current advances in chitosan nanoparticles based oral drug delivery for colorectal cancer treatment

H Choukaife, S Seyam, B Alallam… - International journal …, 2022 - Taylor & Francis
As per the WHO, colorectal cancer (CRC) caused around 935,173 deaths worldwide in 2020
in both sexes and at all ages. The available anticancer therapies including chemotherapy …

Clinical applications of nanomedicine in cancer therapy

M Norouzi, M Amerian, M Amerian, F Atyabi - Drug discovery today, 2020 - Elsevier
Cancer incidence and mortality are rapidly growing worldwide. In attempts to develop more
efficacious therapeutic regimens for patients with cancer, nanomedicines have found …

A concise review on cancer treatment methods and delivery systems

E Bidram, Y Esmaeili, H Ranji-Burachaloo… - Journal of Drug Delivery …, 2019 - Elsevier
The ultimate purpose of current cancer research is to develop a comprehensive treatment for
cancer. Recent studies have shown an increased interest in investigating the capacity of …

Application of smart solid lipid nanoparticles to enhance the efficacy of 5-fluorouracil in the treatment of colorectal cancer

T Smith, K Affram, EL Nottingham, B Han, F Amissah… - Scientific reports, 2020 - nature.com
Fluorouracil (5-FU) is a standard treatment option for colorectal cancer (CRC) but its rapid
metabolism and systemic instability (short half-life) has hindered its therapeutic efficacy. The …

Synthesis of 5-fluorouracil cocrystals with novel organic acids as coformers and anticancer evaluation against HCT-116 colorectal cell lines

F Jubeen, A Liaqat, F Amjad, M Sultan… - Crystal Growth & …, 2020 - ACS Publications
5-Fluorouracil (5-FU) being a mainstream anticancer drug is under keen and detailed
investigation for prodrugs formulations in order to minimize the associated side effects …

[HTML][HTML] Polymeric nanocarriers: A promising tool for early diagnosis and efficient treatment of colorectal cancer

M Haider, KZ Zaki, MR El Hamshary, Z Hussain… - Journal of advanced …, 2022 - Elsevier
Background Colorectal cancer (CRC) is the third most prevalent type of cancer for incidence
and second for mortality worldwide. Late diagnosis and inconvenient and expensive current …

Insight into novel β-cyclodextrin-grafted-poly (N-vinylcaprolactam) nanogel structures as advanced carriers for 5-fluorouracil: Equilibrium behavior and …

HM El-Zeiny, MR Abukhadra, OM Sayed… - Colloids and Surfaces A …, 2020 - Elsevier
Novel β-cyclodextrin-grafted-N-vinylcaprolactam nanogel structures (β-CD-g-PNVCL NG)
were synthesized with different ratios by free radical graft copolymerization in aqueous …

Green encapsulation of LDH (Zn/Al)-5-Fu with carboxymethyl cellulose biopolymer; new nanovehicle for oral colorectal cancer treatment

M Pooresmaeil, SB Nia, H Namazi - International journal of biological …, 2019 - Elsevier
Due to the decrease of the drugs side effects in controlled drug delivery systems, today's
many research has been focused on designing the new controlled drug delivery systems …

Insight into the loading and release properties of an exfoliated kaolinite/cellulose fiber (EXK/CF) composite as a carrier for oxaliplatin drug: Cytotoxicity and release …

L Tian, MR Abukhadra, AS Mohamed, A Nadeem… - ACS …, 2020 - ACS Publications
Kaolinite layers were exfoliated as single sheets and admixed with cellulose fibers, forming
an advanced exfoliated kaolinite/cellulose fiber (EXK/CF) composite, which was …