For decades infections have been treated easily with drugs. However, in the 21st century,
they may become lethal again owing to the development of antimicrobial resistance …

Nanomedicine is an emerging and rapidly evolving field and includes the use of
nanoparticles for diagnosis and therapy of a variety of diseases, as well as in regenerative …

Nanomedicine is an interdisciplinary research field that results from the application of
nanotechnology to medicine and has the potential to significantly improve some current …

The major causative agent of tuberculosis (TB), ie, Mycobacterium tuberculosis (Mtb), has
developed mechanisms to evade host defense responses and persist within host cells for …

Despite co-evolving with humans for centuries and being intensely studied for decades, the
immune correlates of protection against Mycobacterium tuberculosis (Mtb) have yet to be …

Polymeric nanoparticles have been widely investigated as a controlled release drug delivery
platform for the treatment of tuberculosis (TB). These nanoparticles are readily internalised …

Aim: This work aims to develop a mannosylated nanostructured lipid carrier (NLC) loaded
with rifampicin to improve tuberculosis treatment. Materials & methods: An active targeting …

Nanomaterials are utilized in a wide array of end user products such as pharmaceuticals,
electronics, clothes and cosmetic products. Due to its size (< 100 nm), nanoparticles have …

Purpose There is significant interest in the application of nanoparticles to deliver
immunostimulatory signals to cells. We hypothesized that curdlan (immune stimulating …

Nanoparticles (NPs) that can activate macrophages infected with the tuberculosis causative
pathogen Mycobacterium tuberculosis, could be an effective host directed therapy for the …