For centuries, novel strains of influenza have emerged to produce human pandemics,
causing widespread illness, death, and disruption. There have been four influenza …

AS03 is an Adjuvant System composed of α-tocopherol, squalene and polysorbate 80 in an
oil-in-water emulsion. In various nonclinical and clinical studies, high levels of antigen …

While therapeutic drugs are routinely self-administered by patients, there is little precedent
for self-vaccination. Convenient self-vaccination may expand vaccination coverage and …

Background Seasonal influenza immunization programs vary widely across jurisdictions. In
Canada, some provinces offer universal programs while others target specific population …

Background While the H1N1v influenza pandemic in 2009 was clinically mild, with a low
case-fatality rate, the overall disease burden measured in quality-adjusted life years (QALY) …

Solar ultraviolet (UV) radiation is the second most prevalent carcinogenic exposure in
Canada and is similarly important in other countries with large Caucasian populations. The …

Background The present study aims to evaluate the cost-effectiveness of extending the pre-
2013 influenza immunisation programme for high-risk and elderly individuals to those at low …

Background Estimates of health‐related quality of life (HRQ oL) and work/school absences
for influenza are typically based on medically attended cases or those meeting influenza …

Seasonal influenza represents a considerable public health burden, and annual vaccination
represents the most effective preventive strategy for amelioration of this problem. Certain …

Context Population-level coverage for immunization against many vaccine-preventable
diseases remains below optimal rates in the US The Community Preventive Services Task …