An increasing number of studies are describing potential uses of circulating tumour DNA
(ctDNA) in the care of patients with colorectal cancer. Owing to this rapidly developing area …

Ferroptosis is a newly recognised type of regulated cell death (RCD) characterised by iron-
dependent accumulation of lipid peroxidation. It is significantly distinct from other RCDs at …

ESGE recommends that the evaluation of superficial gastrointestinal (GI) lesions should be
made by an experienced endoscopist, using high definition white-light and …

PURPOSE BEACON CRC evaluated encorafenib plus cetuximab with or without binimetinib
versus investigators' choice of irinotecan or FOLFIRI plus cetuximab in patients with …

The following recommendations for post-polypectomy colonoscopic surveillance apply to all
patients who had one or more polyps that were completely removed during a high quality …

Several decades ago, colorectal cancer was infrequently diagnosed. Nowadays, it is the
world's fourth most deadly cancer with almost 900 000 deaths annually. Besides an ageing …

Tumor-infiltrating lymphocytes (TILs) are an important histopathologic feature of colorectal
cancer that confer prognostic information. Previous clinical and epidemiologic studies have …

Ferroptosis, a type of cell death triggered by excessive accumulation of iron-dependent lipid
peroxidation, possesses an excellent potential in cancer treatment. However, many …

Deep learning (DL) can accelerate the prediction of prognostic biomarkers from routine
pathology slides in colorectal cancer (CRC). However, current approaches rely on …

Purpose: Regorafenib is synergistic with immune checkpoint inhibition in colorectal cancer
preclinical models. Patients and Methods: This was a single-arm, multicentric phase II trial …