According to emerging studies, the excessive activation of microglia and the subsequent
release of pro-inflammatory cytokines play important roles in the pathogenesis and …

Parkinson's disease (PD) is one of the most debilitating brain diseases. Despite the
availability of symptomatic treatments, response towards the health of PD patients remains …

Abstract Parkinson's disease (PD), known as one of the most universal neurodegenerative
diseases, is a serious threat to the health of the elderly. The current treatment has been …

What happens precociously to the brain destined to develop Alzheimer's Disease (AD) still
remains to be elucidated and this is one reason why effective AD treatments are missing …

Parkinson's disease (PD) is a neurodegenerative disorder pathologically distinguished by
degeneration of dopaminergic neurons in the substantia nigra pars compacta. Muscle …

Parkinson's disease (PD) comprises a spectrum of disorders with differing subtypes, the vast
majority of which share Lewy bodies (LB) as a characteristic pathological hallmark. The …

Differentiated status, low regenerative capacity and complex signaling make neuronal
tissues highly susceptible to translating an imbalance in cell homeostasis into cell death …

Parkinson's disease (PD) is the second most prevalent neurodegenerative disease of the
central nervous system, with an estimated 5 000 000 cases worldwide. Historically …

Parkinson's disease (PD) significantly affects patients' quality of life and represents a high
economic burden for health systems. Given the lack of safe and effective treatments for PD …

Alzheimer's disease (AD) is an incurable neurodegenerative disorder with a few early
detection strategies. We previously proposed the amyloid precursor protein (APP) tyrosine …