Humans have a close phylogenetic relationship with nonhuman primates (NHPs) and share
many physiological parallels, such as highly similar immune systems, with them. Importantly …

Macaques provide the most widely used nonhuman primate models for studying the
immunology and pathogenesis of human diseases. Although the macaque major …

Although the low polymorphism of the major histocompatibility complex (MHC)
transplantation genes in the Filipino cynomolgus macaque (Macaca fascicularis) is expected …

The role of sex-specific demography in hybridization and admixture of genetically diverged
species and populations is essential to understand the origins of the genomic diversity of …

Background Human chromosome 19 has many unique characteristics including gene
density more than double the genome-wide average and 20 large tandemly clustered gene …

Cynomolgus macaques (Macaca fascicularis) were introduced to the island of Mauritius by
humans around the 16th century. The unique demographic history of the Mauritian …

Primates display a wide range of phenotypic variation underlaid by complex genetically
regulated mechanisms. The links among DNA sequence, gene function, and phenotype …

Sustainable HIV remission after antiretroviral therapy (ART) withdrawal, or post-treatment
control (PTC), remains a top priority for HIV treatment. We observed surprising PTC in an …

ABSTRACT BLT (bone marrow-liver-thymus) humanized mice, which reconstitute a
functional human immune system, develop prototypic human virus-specific CD8+ T cell …

Tuberculosis (TB), caused by Mycobacterium tuberculosis, is the leading cause of death
among human immunodeficiency virus (HIV)-positive patients. The precise mechanisms by …