[HTML][HTML] What is the impact of human umbilical cord mesenchymal stem cell transplantation on clinical treatment?

Q Xie, R Liu, J Jiang, J Peng, C Yang, W Zhang… - Stem cell research & …, 2020 - Springer
Background Human umbilical cord mesenchymal stem cells (HUC-MSCs) present in the
umbilical cord tissue are self-renewing and multipotent. They can renew themselves …

[HTML][HTML] The potential use of mesenchymal stem cells and their derived exosomes for orthopedic diseases treatment

K Malekpour, A Hazrati, M Zahar, A Markov… - Stem cell reviews and …, 2022 - Springer
Musculoskeletal disorders (MSDs) are conditions that can affect muscles, bones, and joints.
These disorders are very painful and severely limit patients' mobility and are more common …

Characteristics and clinical applications of Wharton's jelly-derived mesenchymal stromal cells

LL Liau, BHI Ruszymah, MH Ng, JX Law - Current research in translational …, 2020 - Elsevier
Mesenchymal stromal cells (MSCs) are widely used in the clinic because they involve fewer
ethical issues and safety concerns compared to other stem cells such as embryonic stem …

Single‐cell and spatial transcriptomics decodes Wharton's jelly‐derived mesenchymal stem cells heterogeneity and a subpopulation with wound repair signatures

P Chen, S Tang, M Li, D Wang, C Chen… - Advanced …, 2023 - Wiley Online Library
The highly heterogeneous characteristics of Wharton's jelly mesenchymal stem cells (WJ‐
MSCs) may be responsible for the poor clinical outcomes and poor reproducibility of …

[HTML][HTML] Extracellular vesicles derived from human Wharton's jelly mesenchymal stem cells protect hippocampal neurons from oxidative stress and synapse damage …

V Bodart-Santos, LRP de Carvalho… - Stem cell research & …, 2019 - Springer
Abstract Background Mesenchymal stem cells (MSCs) have been explored as promising
tools for treatment of several neurological and neurodegenerative diseases. MSCs release …

Progress and emerging techniques for biomaterial-based derivation of mesenchymal stem cells (MSCs) from pluripotent stem cells (PSCs)

N Prakash, J Kim, J Jeon, S Kim, Y Arai… - Biomaterials …, 2023 - spj.science.org
The use of mesenchymal stem cells (MSCs) for clinical purposes has skyrocketed in the past
decade. Their multilineage differentiation potentials and immunomodulatory properties have …

An In Vitro and In Vivo Comparison of Osteogenic Differentiation of Human Mesenchymal Stromal/Stem Cells

J Mollentze, C Durandt, MS Pepper - Stem cells international, 2021 - Wiley Online Library
The use of stem cells in regenerative medicine, including tissue engineering and
transplantation, has generated a great deal of enthusiasm. Mesenchymal stromal/stem cells …

[HTML][HTML] Human Wharton's jelly—cellular specificity, stemness potency, animal models, and current application in human clinical trials

K Stefańska, K Ożegowska, G Hutchings… - Journal of Clinical …, 2020 - mdpi.com
Stem cell therapies offer a great promise for regenerative and reconstructive medicine, due
to their self-renewal and differentiation capacity. Although embryonic stem cells are …

NANOG expression in human development and cancerogenesis

G Grubelnik, E Boštjančič, A Pavlič… - Experimental …, 2020 - journals.sagepub.com
NANOG is an important stem cell transcription factor involved in human development and
cancerogenesis. Its expression is complex and regulated on different levels. Moreover …

Sources, characteristics, and therapeutic applications of mesenchymal cells in tissue engineering

RA Gonzalez-Vilchis, A Piedra-Ramirez… - Tissue Engineering and …, 2022 - Springer
Tissue engineering (TE) is a therapeutic option within regenerative medicine that allows to
mimic the original cell environment and functional organization of the cell types necessary …