Iron deficiency and immune activation are the two most frequent causes of anemia, both of
which are based on disturbances of iron homeostasis. Iron deficiency anemia results from a …

Anemia is associated with increased morbidity and mortality in older adults. Diagnostic cutoff
values for defining anemia vary with age, sex, and possibly race. Anemia is often …

For the first time, a paper-based analytical device (PAD) was developed for the assessment
of transferrin saturation (TSAT), which is defined as the ratio between iron bound to …

Justification Anemia in children is a significant public health problem in our country.
Comprehensive National Nutrition Survey 2016–18 provides evidence that more than 50 …

Intravenous iron-carbohydrate complex preparations (IVIP) are noninterchangeable pro-
drugs: their pharmacokinetics (PK) varies determined by semi-crystalline iron core and …

Despite transferrin being the main circulating carrier of iron in body fluids, and iron overload
conditions being known to worsen stroke outcome through reactive oxygen species (ROS) …

Iron deficiency anemia affects approximately 45% of patients with inflammatory bowel
disease (IBD), negatively impacts the quality of life in this patient population, and …

A novel microfluidic paper-based analytical device with dual colorimetric and
electrochemical detection (dual μPAD) was developed for the assessment of transferrin …

TMPRSS6 variants that affect protein function result in impaired matriptase‐2 function and
consequently uninhibited hepcidin production, leading to iron refractory iron deficiency …

There are numerous blood-based biomarkers for assessing iron stores, but all come with
certain limitations. Hepcidin is a hormone primarily produced in the liver that has been …