Molecular mechanisms of western diet-induced obesity and obesity-related carcinogenesis—A narrative review

D Lathigara, D Kaushal, RB Wilson - Metabolites, 2023 - mdpi.com
The present study aims to provide a narrative review of the molecular mechanisms of
Western diet-induced obesity and obesity-related carcinogenesis. A literature search of the …

Recent progress in epigenetics of obesity

FY Wu, RX Yin - Diabetology & Metabolic Syndrome, 2022 - Springer
Nowadays, obesity is one of the largest public health problems worldwide. In the last few
decades, there has been a marked increase in the obesity epidemic and its related …

RNA-based therapies: A cog in the wheel of lung cancer defense

P Khan, JA Siddiqui, I Lakshmanan, AK Ganti, R Salgia… - Molecular cancer, 2021 - Springer
Lung cancer (LC) is a heterogeneous disease consisting mainly of two subtypes, non-small
cell lung cancer (NSCLC) and small cell lung cancer (SCLC), and remains the leading …

Metabolic and epigenetic regulation by estrogen in adipocytes

JI Bjune, PP Strømland, RÅ Jersin… - Frontiers in …, 2022 - frontiersin.org
Sex hormones contribute to differences between males and females in body fat distribution
and associated disease risk. Higher concentrations of estrogens are associated with a more …

Connecting the dots in the associations between diet, obesity, cancer, and microRNAs

K Otsuka, H Nishiyama, D Kuriki, N Kawada… - Seminars in cancer …, 2023 - Elsevier
The prevalence of obesity has reached pandemic levels worldwide, leading to a lower
quality of life and higher health costs. Obesity is a major risk factor for noncommunicable …

Factors of obesity and metabolically healthy obesity in Asia

BJ Mathis, K Tanaka, Y Hiramatsu - Medicina, 2022 - mdpi.com
The East Asian region (China, Japan, and South Korea) is comprised of almost 1.5 billion
people and recent industrialization has brought with it a pandemic of rising obesity, even in …

MicroRNAs: a crossroad that connects obesity to immunity and aging

A Rakib, S Kiran, M Mandal, UP Singh - Immunity & Ageing, 2022 - Springer
Obesity is characterized by an elevated amount of fat and energy storage in the adipose
tissue (AT) and is believed to be the root cause of many metabolic diseases (MDs). Obesity …

Obesity, obesities and gastrointestinal cancers

Y Zou, CS Pitchumoni - Disease-a-Month, 2023 - Elsevier
Obesity has been recognized to be increasing globally and is designated a disease with
adverse consequences requiring early detection and appropriate care. In addition to being …

Message transmission between adipocyte and macrophage in obesity

AB Engin - Obesity and Lipotoxicity, 2024 - Springer
Obesity is characterized by the chronic low-grade activation of the innate immune system. In
this respect, macrophage-elicited metabolic inflammation and adipocyte–macrophage …

Lipid nanoparticles as a shuttle for anti-adipogenic miRNAs to human adipocytes

AL Schachner-Nedherer, J Fuchs, I Vidakovic, O Höller… - Pharmaceutics, 2023 - mdpi.com
Obesity and type 2 diabetes are major health burdens for which no effective therapy is
available today. One treatment strategy could be to balance the metabolic functions of …