Explosive advances in next‐generation sequencer (NGS) and computational analyses have
enabled exploration of somatic protein‐altered mutations in most cancer types, with coding …

MYC regulates a complex biological program by transcriptionally activating and repressing
its numerous target genes. As such, MYC is a master regulator of many processes, including …

The advent of Next-Generation Sequencing (NGS) technologies has opened new
perspectives in deciphering the genetic mechanisms underlying complex diseases …

Next generation sequencing (NGS) has been an invaluable tool to put genomic sequencing
into clinical practice. The incorporation of clinically relevant target sequences into NGS …

Ribosomes are cellular machines essential for protein synthesis. The biogenesis of
ribosomes is a highly complex and energy consuming process that initiates in the nucleolus …

The outbreak of COVID-19 has positively impacted the NGS market recently. Targeted
sequencing (TS) has become an important routine technique in both clinical and research …

Natural products with polypharmacological profiles have demonstrated promise as novel
therapeutics for various complex diseases, including cancer. Currently, many gaps exist in …

Importance Newborn genomic sequencing (nGS) may provide health benefits throughout
the life span, but there are concerns that it could also have an unfavorable (ie, negative) …

The rapid advancement of high-throughput technologies, particularly next-generation
sequencing (NGS), has revolutionized cancer research by enabling the investigation of …

Background The use of genome-wide (whole genome or exome) sequencing for population-
based newborn screening presents an opportunity to detect and treat or prevent many more …